Jesse C. Nussbaum

Infectious Disease

513 Parnassus Ave
San Francisco, CA 94143

Last Updated: 09/26/2026

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Found 28 publications

First-in-human safety and pharmacokinetics of MK-7602, the antimalarial inhibitor of plasmepsins IX/X, in single- and multiple-ascending-dose studies.

First-in-human safety and pharmacokinetics of MK-7602, the antimalarial inhibitor of plasmepsins IX/X, in single- and multiple-ascending-dose studies.

Journal: Antimicrobial agents and chemotherapy

Published: January 14, 2026

Gefapixant as a P2X3 receptor antagonist treatment for obstructive sleep apnea: a randomized controlled trial.

Gefapixant as a P2X3 receptor antagonist treatment for obstructive sleep apnea: a randomized controlled trial.

Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Published: July 29, 2024

Single- and Multiple-Dose Pharmacokinetics of Gefapixant (MK-7264), a P2X3 Receptor Antagonist, in Healthy Adults.

Single- and Multiple-Dose Pharmacokinetics of Gefapixant (MK-7264), a P2X3 Receptor Antagonist, in Healthy Adults.

Journal: Journal of clinical pharmacology

Published: November 20, 2023

Considerations for Cell and Gene Therapy Programs Entering the Clinical Space.

Considerations for Cell and Gene Therapy Programs Entering the Clinical Space.

Journal: Clinical pharmacology and therapeutics

Published: April 13, 2023

Population pharmacokinetic analysis of the P2X3-receptor antagonist gefapixant.

Population pharmacokinetic analysis of the P2X3-receptor antagonist gefapixant.

Journal: CPT: pharmacometrics & systems pharmacology

Published: April 03, 2023

Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults.

Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults.

Journal: Vaccine

Published: March 23, 2023

International consortium for innovation and quality: An industry perspective on the nonclinical and early clinical development of intravitreal drugs.

International consortium for innovation and quality: An industry perspective on the nonclinical and early clinical development of intravitreal drugs.

Journal: Clinical and translational science

Published: September 26, 2022

Effects of Renal Impairment on the Pharmacokinetics of Gefapixant, a P2X3 Receptor Antagonist.

Effects of Renal Impairment on the Pharmacokinetics of Gefapixant, a P2X3 Receptor Antagonist.

Journal: Journal of clinical pharmacology

Published: March 04, 2022

A Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of 3 Weeks of Orally Administered Gefapixant in Healthy Younger and Older Adults.

A Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of 3 Weeks of Orally Administered Gefapixant in Healthy Younger and Older Adults.

Journal: Lung

Published: February 28, 2022

Characterization of the absorption, metabolism, excretion, and mass balance of gefapixant in humans.

Characterization of the absorption, metabolism, excretion, and mass balance of gefapixant in humans.

Journal: Pharmacology research & perspectives

Published: January 10, 2022

Clinical Formulation Bridging of Gefapixant, a P2X3-Receptor Antagonist, for the Treatment of Chronic Cough.

Clinical Formulation Bridging of Gefapixant, a P2X3-Receptor Antagonist, for the Treatment of Chronic Cough.

Journal: Clinical pharmacology in drug development

Published: January 07, 2022

Assessment of the Effect of Pyrimethamine, a Potent Inhibitor of Multidrug and Toxin Extrusion Protein 1/2K, on the Pharmacokinetics of Gefapixant (MK-7264), a P2X3 Receptor Antagonist.

Assessment of the Effect of Pyrimethamine, a Potent Inhibitor of Multidrug and Toxin Extrusion Protein 1/2K, on the Pharmacokinetics of Gefapixant (MK-7264), a P2X3 Receptor Antagonist.

Journal: Clinical pharmacology in drug development

Published: April 19, 2021

Showing 1-12 of 28

Last Updated: 09/26/2026