Last Updated: 09/26/2026
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Found 13 publications
Rapid Optimization Enabled by Single-Molecule Tracking: Discovery of a Potent RUVBL1/2 Inhibitor to Evaluate the Targeting of MYC-Driven Cancers.
Journal: Journal of medicinal chemistry
Published: April 22, 2026
Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs.
Journal: Molecular cancer therapeutics
Published: March 08, 2022
VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy.
Journal: Journal of translational medicine
Published: August 21, 2021
A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6.
Journal: The Journal of pharmacology and experimental therapeutics
Published: December 26, 2020
Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.
Journal: Science translational medicine
Published: December 12, 2020
CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity.
Journal: ACS chemical biology
Published: January 15, 2019
Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 08, 2017
Signaling via the NFκB system.
Journal: Wiley interdisciplinary reviews. Systems biology and medicine
Published: October 25, 2015
Anatomy of a negative feedback loop: the case of IκBα.
Journal: Journal of the Royal Society, Interface
Published: August 28, 2015
A multi-scale approach reveals that NF-κB cRel enforces a B-cell decision to divide.
Journal: Molecular systems biology
Published: February 15, 2015
Limited specificity of IRF3 and ISGF3 in the transcriptional innate-immune response to double-stranded RNA.
Journal: Journal of leukocyte biology
Published: October 14, 2014
Network dynamics determine the autocrine and paracrine signaling functions of TNF.
Journal: Genes & development
Published: October 03, 2014
Last Updated: 09/26/2026