Jesus Florez

Santander, CB, Spain

Last Updated: 09/26/2026

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Found 9 publications

The history of Down syndrome-associated Alzheimer's disease; past, present, and future.

The history of Down syndrome-associated Alzheimer's disease; past, present, and future.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: January 26, 2025

Translational validity and implications of pharmacotherapies in preclinical models of Down syndrome.

Translational validity and implications of pharmacotherapies in preclinical models of Down syndrome.

Journal: Progress in brain research

Published: February 15, 2020

The Koolen-de Vries syndrome: a phenotypic comparison of patients with a 17q21.31 microdeletion versus a KANSL1 sequence variant.

The Koolen-de Vries syndrome: a phenotypic comparison of patients with a 17q21.31 microdeletion versus a KANSL1 sequence variant.

Journal: European journal of human genetics : EJHG

Published: April 28, 2015

Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome.

Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome.

Journal: PloS one

Published: April 24, 2014

Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.

Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.

Journal: Journal of pineal research

Published: August 12, 2013

Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.

Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: March 01, 2013

Apoptosis in Down's syndrome: lessons from studies of human and mouse models.

Apoptosis in Down's syndrome: lessons from studies of human and mouse models.

Journal: Apoptosis : an international journal on programmed cell death

Published: December 11, 2012

Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome.

Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndrome.

Journal: Journal of pineal research

Published: August 15, 2012

Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities.

Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities.

Journal: Neural plasticity

Published: January 19, 2012

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Last Updated: 09/26/2026