Jia X. Yu
550025, China
Last Updated: 09/26/2026
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Found 58 publications
Structure-optimized 4-trifluoromethylquinoline derivatives: Dual enhancement of SGK1 inhibition and anti-prostate cancer efficacy.
Journal: Bioorganic chemistry
Published: February 26, 2026
A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms.
Journal: iScience
Published: February 25, 2026
Design, synthesis, and anti-prostate cancer activity evaluation of novel thieno[2,3-b]pyridine derivatives as potential BLM helicase inhibitors.
Journal: Molecular diversity
Published: February 14, 2026
Astragalus polysaccharides alleviate cantharidin-induced liver injury by inhibiting the S100A8/A9-mediated TLR4/NF-κB inflammatory pathway.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Published: February 12, 2026
Alleviating Effects of Zophobas morio and Tenebrio molitor Larvae Protein Powder on Dextran Sodium Sulfate-Induced Inflammatory Bowel Disease in Mice.
Journal: International journal of molecular sciences
Published: December 23, 2025
A Trifluoromethyl Quinazoline Compound Regulates the Epithelial-Mesenchymal Transition of Prostatic Hyperplasia Cells by Inhibiting the Secretion of TGF-β1 in Stromal Cells.
Journal: Current issues in molecular biology
Published: November 20, 2025
A trifluoromethyl quinoline derivative targets SGK1 and modulates the PI3K/AKT pathway to inhibit prostate cancer progression.
Journal: Medical oncology (Northwood, London, England)
Published: September 28, 2025
The fluoroquinoline compound exerts anti-erythroleukemic effects by dual-targeting GLUT1 and the PI3K/AKT signaling pathway.
Journal: Scientific reports
Published: September 25, 2025
Novel trifluoromethylquinoline derivatives as potent tubulin polymerization inhibitors with antitumor activity.
Journal: Bioorganic & medicinal chemistry
Published: August 07, 2025
Lactate-mediated macrophage polarization promotes splenomegaly in acute erythroleukemia.
Journal: Cell death & disease
Published: July 29, 2025
RECQL4 as a novel drug target against ovarian cancer.
Journal: Biochemical pharmacology
Published: June 10, 2025
Last Updated: 09/26/2026