Jia-xuan Chen

Mainz, RP, Germany

Last Updated: 09/26/2026

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Found 22 publications

The Host Cell Factor Phosphatase-2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type-1.

The Host Cell Factor Phosphatase-2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type-1.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: November 22, 2025

Identification of a Proteolysis-Targeting-Chimera that Addresses Activated Checkpoint Kinase-1 Reveals its Non-Catalytic Functions in Tumor Cells.

Identification of a Proteolysis-Targeting-Chimera that Addresses Activated Checkpoint Kinase-1 Reveals its Non-Catalytic Functions in Tumor Cells.

Journal: Angewandte Chemie (International ed. in English)

Published: July 07, 2025

Interplay of the ENS and Microbiota With Murine Gut Epithelium-Derived Organoids in Aging.

Interplay of the ENS and Microbiota With Murine Gut Epithelium-Derived Organoids in Aging.

Journal: Aging cell

Published: June 20, 2025

Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.

Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2.

Journal: Nature communications

Published: March 31, 2025

The protein deacetylase HDAC10 controls DNA replication in malignant lymphoid cells.

The protein deacetylase HDAC10 controls DNA replication in malignant lymphoid cells.

Journal: Leukemia

Published: November 29, 2024

Poly-GR Impairs PRMT1-Mediated Arginine Methylation of Disease-Linked RNA-Binding Proteins by Acting as a Substrate Sink.

Poly-GR Impairs PRMT1-Mediated Arginine Methylation of Disease-Linked RNA-Binding Proteins by Acting as a Substrate Sink.

Journal: Biochemistry

Published: August 15, 2024

Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease.

Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: February 15, 2024

The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence.

The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence.

Journal: Nucleic acids research

Published: November 09, 2023

Designing photoaffinity tool compounds for the investigation of the DENV NS2B-NS3 protease allosteric binding pocket.

Designing photoaffinity tool compounds for the investigation of the DENV NS2B-NS3 protease allosteric binding pocket.

Journal: RSC medicinal chemistry

Published: July 14, 2023

K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.

K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.

Journal: Molecular cell

Published: April 13, 2023

Ubiquiton-An inducible, linkage-specific polyubiquitylation tool.

Ubiquiton-An inducible, linkage-specific polyubiquitylation tool.

Journal: Molecular cell

Published: April 07, 2023

Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies.

Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies.

Journal: Scientific data

Published: January 19, 2023

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Last Updated: 09/26/2026