Jiacheng He
Haikou, 571199, China
Last Updated: 09/26/2026
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Found 14 publications
Discovery and Characterization of Benzamide Derivatives as Highly Potent SUCNR1 Antagonists for Cancer Immunotherapy.
Journal: Journal of medicinal chemistry
Published: May 08, 2026
Structural mechanisms for self-activation of protease-activated receptor 4 by tethered ligand.
Journal: Cell reports
Published: November 10, 2025
Targeting EP2/EP4-driven expansion of suppressive VSIG4high macrophages overcomes immunotherapy resistance in colorectal cancer.
Journal: Cell reports
Published: September 13, 2025
The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.
Journal: Nature immunology
Published: February 15, 2024
Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy.
Journal: Journal of medicinal chemistry
Published: March 07, 2023
Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia.
Journal: Cell death & disease
Published: August 23, 2022
Scaffold Hopping Strategy to Identify Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy.
Journal: Journal of medicinal chemistry
Published: May 31, 2022
A Novel Small Molecular Prostaglandin Receptor EP4 Antagonist, L001, Suppresses Pancreatic Cancer Metastasis.
Journal: Molecules (Basel, Switzerland)
Published: January 20, 2022
Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer.
Journal: EMBO molecular medicine
Published: June 09, 2020
Shikonin is a novel and selective IMPDH2 inhibitor that target triple-negative breast cancer.
Journal: Phytotherapy research : PTR
Published: March 02, 2020
Last Updated: 09/26/2026