Jiacheng Wei
Shanghai, 200025, China
Last Updated: 09/26/2026
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Found 12 publications
Inhibition of Wnt Signaling Using Axin Peptidomimetics through Direct Targeting of β-Catenin.
Journal: Journal of medicinal chemistry
Published: March 20, 2026
Integrative computational simulations and functional assays decode allosteric dysregulation in a pathogenic SIRT6 variant.
Journal: International journal of biological macromolecules
Published: November 06, 2025
Mechanistic basis of N-terminal domain-mediated allostery in SIRT6: integrating molecular dynamics simulations and biochemical assays.
Journal: Molecular diversity
Published: July 03, 2025
In silico identification and experimental validation of long-range allosteric inhibition of Staphylococcus aureus Cas9 catalytic activity by an anti-CRISPR protein AcrIIA14.
Journal: International journal of biological macromolecules
Published: February 13, 2025
ASD2023: towards the integrating landscapes of allosteric knowledgebase.
Journal: Nucleic acids research
Published: August 21, 2023
DeepAlloDriver: a deep learning-based strategy to predict cancer driver mutations.
Journal: Nucleic acids research
Published: February 19, 2023
AlloReverse: multiscale understanding among hierarchical allosteric regulations.
Journal: Nucleic acids research
Published: February 07, 2023
Rational design of a sensitivity-enhanced tracer for discovering efficient APC-Asef inhibitors.
Journal: Nature communications
Published: November 25, 2021
Discovery of cryptic allosteric sites using reversed allosteric communication by a combined computational and experimental strategy.
Journal: Chemical science
Published: June 24, 2021
Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells.
Journal: Acta pharmaceutica Sinica. B
Published: May 17, 2021
Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators.
Journal: Acta pharmaceutica Sinica. B
Published: August 17, 2020
Small-molecule activating SIRT6 elicits therapeutic effects and synergistically promotes anti-tumor activity of vitamin D3 in colorectal cancer.
Journal: Theranostics
Published: January 17, 2020
Showing 1-12 of 12
Last Updated: 09/26/2026