Jian-hua Ding

Jiangsu Key Laboratory Of Neurodegeneration
Nanjing, 211166, China

Last Updated: 09/26/2026

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Found 42 publications

G protein-coupled receptor 75 mediates depression-like behaviors and HPA axis hyperactivity through an excitatory arcuate-paraventricular nucleus circuit.

G protein-coupled receptor 75 mediates depression-like behaviors and HPA axis hyperactivity through an excitatory arcuate-paraventricular nucleus circuit.

Journal: Acta pharmacologica Sinica

Published: November 25, 2025

Upregulated PKM2 Protects Dopaminergic Neurons From Oxidative Damage Through Nrf2 Transactivation in an MPTP-Induced Mouse Model of Parkinson's Disease.

Upregulated PKM2 Protects Dopaminergic Neurons From Oxidative Damage Through Nrf2 Transactivation in an MPTP-Induced Mouse Model of Parkinson's Disease.

Journal: CNS neuroscience & therapeutics

Published: September 30, 2025

Neuroprotective effect of astrocytic dopamine Drd2 receptor on mitochondrial complex I in a mouse model of Parkinson's disease through β-arrestin2-NDUFA10 regulation.

Neuroprotective effect of astrocytic dopamine Drd2 receptor on mitochondrial complex I in a mouse model of Parkinson's disease through β-arrestin2-NDUFA10 regulation.

Journal: Cell death and differentiation

Published: July 15, 2025

Visceral adipose tissue-derived extracellular vesicles promote stress susceptibility in obese mice via miR-140-5p.

Visceral adipose tissue-derived extracellular vesicles promote stress susceptibility in obese mice via miR-140-5p.

Journal: Acta pharmacologica Sinica

Published: September 06, 2024

The marine-derived compound TAG alleviates Parkinson's disease by restoring RUBCN-mediated lipid metabolism homeostasis.

The marine-derived compound TAG alleviates Parkinson's disease by restoring RUBCN-mediated lipid metabolism homeostasis.

Journal: Acta pharmacologica Sinica

Published: September 12, 2023

Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1.

Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1.

Journal: CNS neuroscience & therapeutics

Published: May 22, 2022

Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway.

Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway.

Journal: Acta pharmacologica Sinica

Published: May 16, 2022

Astrocytic Kir6.1 deletion aggravates neurodegeneration in the lipopolysaccharide-induced mouse model of Parkinson's disease via astrocyte-neuron cross talk through complement C3-C3R signaling.

Astrocytic Kir6.1 deletion aggravates neurodegeneration in the lipopolysaccharide-induced mouse model of Parkinson's disease via astrocyte-neuron cross talk through complement C3-C3R signaling.

Journal: Brain, behavior, and immunity

Published: December 11, 2020

β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression.

β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression.

Journal: Acta pharmacologica Sinica

Published: August 31, 2020

Astragaloside IV inhibits astrocyte senescence: implication in Parkinson's disease.

Astragaloside IV inhibits astrocyte senescence: implication in Parkinson's disease.

Journal: Journal of neuroinflammation

Published: November 02, 2019

Kir6.1/K-ATP channel on astrocytes protects against dopaminergic neurodegeneration in the MPTP mouse model of Parkinson's disease via promoting mitophagy.

Kir6.1/K-ATP channel on astrocytes protects against dopaminergic neurodegeneration in the MPTP mouse model of Parkinson's disease via promoting mitophagy.

Journal: Brain, behavior, and immunity

Published: May 13, 2019

The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3.

The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3.

Journal: Experimental & molecular medicine

Published: November 19, 2018

Showing 1-12 of 42

Last Updated: 09/26/2026