Jian Kang

10 Kent Ridge Crescent, 119260
Kent Ridge, Singapore

Last Updated: 09/26/2026

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Found 18 publications

Extreme diversity of 12 cations in folding ALS-linked hSOD1 unveils novel hSOD1-dependent mechanisms for Fe2+/Cu2+-induced cytotoxicity.

Extreme diversity of 12 cations in folding ALS-linked hSOD1 unveils novel hSOD1-dependent mechanisms for Fe2+/Cu2+-induced cytotoxicity.

Journal: Scientific reports

Published: September 04, 2023

ATP induces folding of ALS-causing C71G-hPFN1 and nascent hSOD1.

ATP induces folding of ALS-causing C71G-hPFN1 and nascent hSOD1.

Journal: Communications chemistry

Published: May 16, 2023

ALS-causing hPFN1 mutants differentially disrupt LLPS of FUS prion-like domain.

ALS-causing hPFN1 mutants differentially disrupt LLPS of FUS prion-like domain.

Journal: Biochemical and biophysical research communications

Published: April 03, 2023

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.

Journal: Nature communications

Published: March 04, 2022

ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues.

ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues.

Journal: Communications biology

Published: November 20, 2020

ATP differentially antagonizes the crowding-induced destabilization of human γS-crystallin and its four cataract-causing mutants.

ATP differentially antagonizes the crowding-induced destabilization of human γS-crystallin and its four cataract-causing mutants.

Journal: Biochemical and biophysical research communications

Published: September 17, 2020

Cataract-causing G18V eliminates the antagonization by ATP against the crowding-induced destabilization of human γS-crystallin.

Cataract-causing G18V eliminates the antagonization by ATP against the crowding-induced destabilization of human γS-crystallin.

Journal: Biochemical and biophysical research communications

Published: July 13, 2020

Surface Enhanced Raman Spectroscopy Based Biosensor with a Microneedle Array for Minimally Invasive In Vivo Glucose Measurements.

Surface Enhanced Raman Spectroscopy Based Biosensor with a Microneedle Array for Minimally Invasive In Vivo Glucose Measurements.

Journal: ACS sensors

Published: May 20, 2020

ATP antagonizes the crowding-induced destabilization of the human eye-lens protein γS-crystallin.

ATP antagonizes the crowding-induced destabilization of the human eye-lens protein γS-crystallin.

Journal: Biochemical and biophysical research communications

Published: April 04, 2020

ATP binds nucleic-acid-binding domains beyond RRM fold.

ATP binds nucleic-acid-binding domains beyond RRM fold.

Journal: Biochemical and biophysical research communications

Published: November 21, 2019

ATP is a cryptic binder of TDP-43 RRM domains to enhance stability and inhibit ALS/AD-associated fibrillation.

ATP is a cryptic binder of TDP-43 RRM domains to enhance stability and inhibit ALS/AD-associated fibrillation.

Journal: Biochemical and biophysical research communications

Published: November 02, 2019

ATP binds and inhibits the neurodegeneration-associated fibrillization of the FUS RRM domain.

ATP binds and inhibits the neurodegeneration-associated fibrillization of the FUS RRM domain.

Journal: Communications biology

Published: February 04, 2019

Showing 1-12 of 18

Last Updated: 09/26/2026