Jianchang Qian

Wenzhou, 325035, China

Last Updated: 09/26/2026

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Found 40 publications

Exploring the antitumor effect of curcumin-piperlongumine hybrid molecule (CP) on EGFR-TKI-resistant non-small cell lung cancer using network pharmacological analysis and experimental verification.

Exploring the antitumor effect of curcumin-piperlongumine hybrid molecule (CP) on EGFR-TKI-resistant non-small cell lung cancer using network pharmacological analysis and experimental verification.

Journal: Acta biochimica et biophysica Sinica

Published: July 10, 2025

Effect of Cytochrome P450 2C9 genetic polymorphism on agomelatine metabolism in vitro.

Effect of Cytochrome P450 2C9 genetic polymorphism on agomelatine metabolism in vitro.

Journal: PeerJ

Published: May 05, 2025

Impact of CYP3A4 functional variability on ziprasidone metabolism.

Impact of CYP3A4 functional variability on ziprasidone metabolism.

Journal: Frontiers in pharmacology

Published: February 28, 2025

Early Evaluation of the Interaction and Gender Differences in Combination of Apatinib and Metoprolol Using Humanized CYP2D6 Model.

Early Evaluation of the Interaction and Gender Differences in Combination of Apatinib and Metoprolol Using Humanized CYP2D6 Model.

Journal: Chemical research in toxicology

Published: January 15, 2025

CYP3A4 and CYP3A5: the crucial roles in clinical drug metabolism and the significant implications of genetic polymorphisms.

CYP3A4 and CYP3A5: the crucial roles in clinical drug metabolism and the significant implications of genetic polymorphisms.

Journal: PeerJ

Published: August 08, 2024

The influence of drug-induced metabolic enzyme activity inhibition and CYP3A4 gene polymorphism on aumolertinib metabolism.

The influence of drug-induced metabolic enzyme activity inhibition and CYP3A4 gene polymorphism on aumolertinib metabolism.

Journal: Frontiers in pharmacology

Published: February 28, 2024

Crizotinib inhibits the metabolism of tramadol by non-competitive suppressing the activities of CYP2D1 and CYP3A2.

Crizotinib inhibits the metabolism of tramadol by non-competitive suppressing the activities of CYP2D1 and CYP3A2.

Journal: PeerJ

Published: February 23, 2024

Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction.

Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction.

Journal: PeerJ

Published: October 17, 2023

Hyperglycemia activates FGFR1 via TLR4/c-Src pathway to induce inflammatory cardiomyopathy in diabetes.

Hyperglycemia activates FGFR1 via TLR4/c-Src pathway to induce inflammatory cardiomyopathy in diabetes.

Journal: Acta pharmaceutica Sinica. B

Published: September 29, 2023

The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism.

The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism.

Journal: PeerJ

Published: August 16, 2023

cyy-287, a novel pyrimidine-2,4-diamine derivative, inhibits tumor growth of EGFR-driven non-small cell lung cancer via the ERK pathway.

cyy-287, a novel pyrimidine-2,4-diamine derivative, inhibits tumor growth of EGFR-driven non-small cell lung cancer via the ERK pathway.

Journal: Acta biochimica et biophysica Sinica

Published: October 14, 2022

Functional evaluation of cyclosporine metabolism by CYP3A4 variants and potential drug interactions.

Functional evaluation of cyclosporine metabolism by CYP3A4 variants and potential drug interactions.

Journal: Frontiers in pharmacology

Published: September 15, 2022

Showing 1-12 of 40

Last Updated: 09/26/2026