Jianchao Zhang

Shenzhen, 518055, China

Last Updated: 09/26/2026

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Found 18 publications

Mighty mini-PROTACs: an emerging class of degraders.

Mighty mini-PROTACs: an emerging class of degraders.

Journal: European journal of medicinal chemistry
Published: August 20, 2025

Targeted degradation of α-synuclein by arginine-based PROTACs.

Targeted degradation of α-synuclein by arginine-based PROTACs.

Journal: The Journal of biological chemistry
Published: May 20, 2025

Linker-free PROTACs efficiently induce the degradation of oncoproteins.

Linker-free PROTACs efficiently induce the degradation of oncoproteins.

Journal: Nature communications
Published: September 22, 2024

Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC).

Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC).

Journal: Journal of medicinal chemistry
Published: August 08, 2024

Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma.

Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma.

Journal: iScience
Published: April 01, 2024

Single amino acid-based PROTACs trigger degradation of the oncogenic kinase BCR-ABL in chronic myeloid leukemia (CML).

Single amino acid-based PROTACs trigger degradation of the oncogenic kinase BCR-ABL in chronic myeloid leukemia (CML).

Journal: The Journal of biological chemistry
Published: April 22, 2023

Natural Compounds, Optimal Combination of Brusatol and Polydatin Promote Anti-Tumor Effect in Breast Cancer by Targeting Nrf2 Signaling Pathway.

Natural Compounds, Optimal Combination of Brusatol and Polydatin Promote Anti-Tumor Effect in Breast Cancer by Targeting Nrf2 Signaling Pathway.

Journal: International journal of molecular sciences
Published: March 15, 2023

The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression.

The PRMT5-LSD1 axis confers Slug dual transcriptional activities and promotes breast cancer progression.

Journal: Journal of experimental & clinical cancer research : CR
Published: February 11, 2022

TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression.

TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression.

Journal: Clinical and translational medicine
Published: July 08, 2021

A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.

A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo.

Journal: Biochemical and biophysical research communications
Published: July 05, 2021

Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.

Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis.

Journal: Oncogene
Published: July 12, 2019

Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.

Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 10, 2019
Showing 1-12 of 18

Last Updated: 09/26/2026