Jianchun Zhao

Qingdao, 266073, China

Last Updated: 09/26/2026

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Found 16 publications

Comprehensive Pharmacokinetics of the Marine-Derived PDE4 Inhibitor LY104 and Its Major Metabolite M1 in Rats: A Validated LC-MS/MS Method with Sex Comparison, Multiple-Dose, Protein Binding, Metabolic Stability, and Excretion Studies.

Comprehensive Pharmacokinetics of the Marine-Derived PDE4 Inhibitor LY104 and Its Major Metabolite M1 in Rats: A Validated LC-MS/MS Method with Sex Comparison, Multiple-Dose, Protein Binding, Metabolic Stability, and Excretion Studies.

Journal: Marine drugs

Published: May 08, 2026

Discovery of Marine-Inspired Guanidine-Based PDE4 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.

Discovery of Marine-Inspired Guanidine-Based PDE4 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.

Journal: Marine drugs

Published: January 30, 2026

Design, synthesis, and anti-cancer evaluation of the novel conjugate of gemcitabine's ProTide prodrug based on CD13.

Design, synthesis, and anti-cancer evaluation of the novel conjugate of gemcitabine's ProTide prodrug based on CD13.

Journal: Bioorganic chemistry

Published: January 13, 2025

Discovery of Novel 2,3-Dihydro-1H-indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis.

Discovery of Novel 2,3-Dihydro-1H-indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis.

Journal: Journal of medicinal chemistry

Published: November 29, 2023

Development and Validation of a Novel UHPLC-MS/MS Method for the Quantification of Plinabulin in Plasma and Its Application in a Pharmacokinetic Study with Leukopenic Rats.

Development and Validation of a Novel UHPLC-MS/MS Method for the Quantification of Plinabulin in Plasma and Its Application in a Pharmacokinetic Study with Leukopenic Rats.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 28, 2023

Investigating the role of E-commerce marketing capabilities to achieve the strategic performance of tourism firms.

Investigating the role of E-commerce marketing capabilities to achieve the strategic performance of tourism firms.

Journal: Frontiers in psychology

Published: November 22, 2022

Comparative Pharmacokinetics and Tissue Distribution of M10 and Its Metabolite Myricetin in Normal and Dextran-Sodium-Sulfate-Induced Colitis Mice.

Comparative Pharmacokinetics and Tissue Distribution of M10 and Its Metabolite Myricetin in Normal and Dextran-Sodium-Sulfate-Induced Colitis Mice.

Journal: Molecules (Basel, Switzerland)

Published: October 18, 2022

Development and validation of LC-MS/MS method for amlexanox in rat plasma and its application in preclinical pharmacokinetics.

Development and validation of LC-MS/MS method for amlexanox in rat plasma and its application in preclinical pharmacokinetics.

Journal: Biomedical chromatography : BMC

Published: August 06, 2021

Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer.

Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer.

Journal: Bioorganic & medicinal chemistry

Published: January 04, 2020

Design, synthesis, and biological evaluation of novel stachydrine derivatives as potent neuroprotective agents for cerebral ischemic stroke.

Design, synthesis, and biological evaluation of novel stachydrine derivatives as potent neuroprotective agents for cerebral ischemic stroke.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: December 19, 2019

Combination of a novel microtubule inhibitor MBRI-001 and gemcitabine synergistically induces cell apoptosis by increasing DNA damage in pancreatic cancer cell lines.

Combination of a novel microtubule inhibitor MBRI-001 and gemcitabine synergistically induces cell apoptosis by increasing DNA damage in pancreatic cancer cell lines.

Journal: Investigational new drugs

Published: August 10, 2019

Development of M10, myricetin-3-O-β-d-lactose sodium salt, a derivative of myricetin as a potent agent of anti-chronic colonic inflammation.

Development of M10, myricetin-3-O-β-d-lactose sodium salt, a derivative of myricetin as a potent agent of anti-chronic colonic inflammation.

Journal: European journal of medicinal chemistry

Published: January 10, 2019

Showing 1-12 of 16

Last Updated: 09/26/2026