Jiankang F. Zhang

Sir Run Run Shaw Hospital, 3 East Qingchun Road
Hangzhou, 310016, China

Last Updated: 09/26/2026

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Found 47 publications

Discovery of novel 20S proteasome activators for hypoxic cardiomyocyte protection via endoplasmic reticulum stress alleviation.

Discovery of novel 20S proteasome activators for hypoxic cardiomyocyte protection via endoplasmic reticulum stress alleviation.

Journal: Bioorganic & medicinal chemistry
Published: August 29, 2025

Synergistic approach utilizing bioinformatics, machine learning, and traditional screening for the identification of novel CSK inhibitors targeting hepatocellular carcinoma.

Synergistic approach utilizing bioinformatics, machine learning, and traditional screening for the identification of novel CSK inhibitors targeting hepatocellular carcinoma.

Journal: Journal of computer-aided molecular design
Published: July 15, 2025

Discovery and characterization of sulfonamide derivatives as transcriptional enhanced associate domain (TEAD) inhibitors: a novel approach for targeting hepatocellular carcinoma.

Discovery and characterization of sulfonamide derivatives as transcriptional enhanced associate domain (TEAD) inhibitors: a novel approach for targeting hepatocellular carcinoma.

Journal: Bioorganic chemistry
Published: June 09, 2025

Discovery and Characterization of Novel FGFR1 V561M Inhibitors via Virtual Screening and Molecular Dynamics Simulations.

Discovery and Characterization of Novel FGFR1 V561M Inhibitors via Virtual Screening and Molecular Dynamics Simulations.

Journal: ACS medicinal chemistry letters
Published: April 09, 2025

Identification of Novel β-Lactam Derivatives as Proteasome Inhibitors for Antitumor Therapy.

Identification of Novel β-Lactam Derivatives as Proteasome Inhibitors for Antitumor Therapy.

Journal: Archiv der Pharmazie
Published: March 19, 2025

Mechanisms underlying altered ubiquitin-proteasome system activity during heart failure and pharmacological interventions.

Mechanisms underlying altered ubiquitin-proteasome system activity during heart failure and pharmacological interventions.

Journal: European journal of medicinal chemistry
Published: March 05, 2025

Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides.

Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides.

Journal: Bioorganic chemistry
Published: December 28, 2024

The Synthesis of Benzazepines via Sequential [3 + 2]-Annulation and [3,3]-Sigmatropic Rearrangement.

The Synthesis of Benzazepines via Sequential [3 + 2]-Annulation and [3,3]-Sigmatropic Rearrangement.

Journal: Organic letters
Published: November 22, 2024

Optimization on the extraction conditions of flavonoids from Suaeda glauca and the research of its hepatoprotection in mice.

Optimization on the extraction conditions of flavonoids from Suaeda glauca and the research of its hepatoprotection in mice.

Journal: Fitoterapia
Published: October 20, 2024

Synthesis of 1,1,3-Polyfunctionalized Cyclobutane Derivatives from the Reaction of Sulfur Ylides with Bicyclo[1.1.0]butanes.

Synthesis of 1,1,3-Polyfunctionalized Cyclobutane Derivatives from the Reaction of Sulfur Ylides with Bicyclo[1.1.0]butanes.

Journal: Organic letters
Published: August 29, 2024

Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection.

Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection.

Journal: Bioorganic & medicinal chemistry
Published: July 13, 2024

DiPTAC: A degradation platform via directly targeting proteasome.

DiPTAC: A degradation platform via directly targeting proteasome.

Journal: Acta pharmaceutica Sinica. B
Published: May 31, 2024
Showing 1-12 of 47

Last Updated: 09/26/2026