Jiannan Chen

Jiangsu Key Laboratory For Molecular And Medical Biotechnology
Nanjing, 210023, China

Last Updated: 09/26/2026

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Found 23 publications

Cascading Attrition of In Vivo CAR-T Therapy: From Systemic Delivery Failure to Functional Collapse.

Cascading Attrition of In Vivo CAR-T Therapy: From Systemic Delivery Failure to Functional Collapse.

Journal: Critical reviews in oncology/hematology
Published: May 26, 2026

Developmental and Neurobehavioral Toxicity of Tetrabromobisphenol A Mono(2-hydroxyethyl) Ether (TBBPA-MHEE) in Zebrafish Larvae: Oxidative/Inflammatory Responses and Candidate ErbB-Related Signaling.

Developmental and Neurobehavioral Toxicity of Tetrabromobisphenol A Mono(2-hydroxyethyl) Ether (TBBPA-MHEE) in Zebrafish Larvae: Oxidative/Inflammatory Responses and Candidate ErbB-Related Signaling.

Journal: Biology
Published: May 24, 2026

Next-Generation CAR-T Therapies: From Personalized Anticancer Drugs to Broadly Applicable Disease-Modifying Treatments.

Next-Generation CAR-T Therapies: From Personalized Anticancer Drugs to Broadly Applicable Disease-Modifying Treatments.

Journal: Transplantation and cellular therapy
Published: April 03, 2026

In Vivo Generation of CAR-T Cells: Current Obstacles, Strategic Solutions, and Clinical Translation.

In Vivo Generation of CAR-T Cells: Current Obstacles, Strategic Solutions, and Clinical Translation.

Journal: Critical reviews in oncology/hematology
Published: March 25, 2026

Oxidative stress in CAR-T cell therapy: Mechanistic insights and redox-targeted interventions.

Oxidative stress in CAR-T cell therapy: Mechanistic insights and redox-targeted interventions.

Journal: Critical reviews in oncology/hematology
Published: October 29, 2025

Envirotune-CAR-T: a hypoxia-responsive and glutamine-enhanced CAR-T cell therapy for overcoming tumor microenvironment-mediated suppression.

Envirotune-CAR-T: a hypoxia-responsive and glutamine-enhanced CAR-T cell therapy for overcoming tumor microenvironment-mediated suppression.

Journal: Journal for immunotherapy of cancer
Published: September 24, 2025

Sodium valproate drives propionylation-mediated epigenetic reprogramming to enhance mesothelin CAR-T cell therapy in solid tumors.

Sodium valproate drives propionylation-mediated epigenetic reprogramming to enhance mesothelin CAR-T cell therapy in solid tumors.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: August 26, 2025

Protein post-translational modifications in CAR-T cells: Novel strategies to amplify antitumor efficacy via epigenetic and metabolic circuitry.

Protein post-translational modifications in CAR-T cells: Novel strategies to amplify antitumor efficacy via epigenetic and metabolic circuitry.

Journal: Critical reviews in oncology/hematology
Published: August 13, 2025

CCR2/CXCR6 enhances tumor infiltration and antitumor efficacy of MSLN CAR-T cells.

CCR2/CXCR6 enhances tumor infiltration and antitumor efficacy of MSLN CAR-T cells.

Journal: Cellular and molecular life sciences : CMLS
Published: July 24, 2025

Microbiota-derived butyrate potentiates MSLN CAR-T cell therapy by metabolic reprogramming and extracellular matrix remodeling.

Microbiota-derived butyrate potentiates MSLN CAR-T cell therapy by metabolic reprogramming and extracellular matrix remodeling.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: June 17, 2025

Bisphenol E Neurotoxicity in Zebrafish Larvae: Effects and Underlying Mechanisms.

Bisphenol E Neurotoxicity in Zebrafish Larvae: Effects and Underlying Mechanisms.

Journal: Biology
Published: June 17, 2025

Glutamine-driven metabolic reprogramming promotes CAR-T cell function through mTOR-SREBP2 mediated HMGCS1 upregulation in ovarian cancer.

Glutamine-driven metabolic reprogramming promotes CAR-T cell function through mTOR-SREBP2 mediated HMGCS1 upregulation in ovarian cancer.

Journal: Journal of translational medicine
Published: May 04, 2025
Showing 1-12 of 23

Last Updated: 09/26/2026