Jianwen Chen
132 E. Wai Huan Rd
Guangzhou, 510006, China
Guangzhou, 510006, China
Last Updated: 09/26/2026
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Found 39 publications
Structure-Based Optimization of Imidazopyridine Derivatives as Selective and Orally Bioavailable Phosphodiesterase 10A Inhibitors with Reduced Blood-Brain Barrier Penetration for the Treatment of Idiopathic Pulmonary Fibrosis.
Journal: Journal of medicinal chemistry
Published: November 21, 2025
Synthesis and anti-acute ischemic stroke effect of quinazoline-benzothiazole RIPK1 inhibitors.
Journal: European journal of medicinal chemistry
Published: September 24, 2025
DST-3, a Novel Modified Cryptotanshinone, Protects Against Pulmonary Fibrosis via Inhibiting STAT3/Smad Signaling Pathway and Improves Bioavailability.
Journal: Pharmaceutics
Published: August 11, 2025
Design, synthesis, anti-acute ischemic stroke (AIS) effect of receptor-interacting protein kinase 1 (RIPK1) inhibitors containing quinazoline structure.
Journal: Bioorganic chemistry
Published: July 21, 2025
DST-3, a novel cryptotanshinone derivate, attenuates glutamate excitotoxicity after ischemic stroke via CREB-Homer1 axis activation.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Published: April 21, 2025
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: April 07, 2025
Phytochemical Analysis and Neuroprotective Effect of Salvia castanea Diels f. Tomentosa Stib Extracts.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: March 31, 2025
The Neuroprotection of 1,2,4-Triazole Derivative by Inhibiting Inflammation and Protecting BBB Integrity in Acute Ischemic Stroke.
Journal: CNS neuroscience & therapeutics
Published: August 07, 2024
Long-term effects of chronic exposure to electronic cigarette aerosol on the cardiovascular and pulmonary system in mice: A comparative study to cigarette smoke.
Journal: Environment international
Published: November 01, 2023
High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT.
Journal: Gut
Published: August 02, 2023
Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB.
Journal: European journal of medicinal chemistry
Published: July 14, 2023
The toxic effects of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal and renal systems in mice.
Journal: Scientific reports
Published: May 05, 2023
Last Updated: 09/26/2026