Jianyou Shi

Personalized Drug Research And Therapy Key Laboratory Of Sichuan Province
Chengdu, China

Last Updated: 09/26/2026

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Found 58 publications

Potential small-molecule tyrosine kinase inhibitors (TKIs) for the treatment of triple-negative breast cancer (TNBC): Targets, structure-activity relationships, and clinical studies.

Potential small-molecule tyrosine kinase inhibitors (TKIs) for the treatment of triple-negative breast cancer (TNBC): Targets, structure-activity relationships, and clinical studies.

Journal: European journal of medicinal chemistry

Published: May 25, 2026

Chemical scaffolds, structure-activity relationships, and therapeutic potential of EphA2 small-molecule inhibitors.

Chemical scaffolds, structure-activity relationships, and therapeutic potential of EphA2 small-molecule inhibitors.

Journal: European journal of medicinal chemistry

Published: April 15, 2026

CZC54252 overcomes Osimertinib resistance by targeting EGFRC797S mutations.

CZC54252 overcomes Osimertinib resistance by targeting EGFRC797S mutations.

Journal: BMC pharmacology & toxicology

Published: October 09, 2025

Deep seeking covalent DNA encoded library for novel JAK3 inhibitor discovery.

Deep seeking covalent DNA encoded library for novel JAK3 inhibitor discovery.

Journal: Bioorganic & medicinal chemistry

Published: August 01, 2025

The impact of STAiR18 on multiple myeloma survival rates.

The impact of STAiR18 on multiple myeloma survival rates.

Journal: Journal of translational medicine

Published: July 23, 2025

Advances in targeting glycogen synthase kinase 3β for diabetes therapy.

Advances in targeting glycogen synthase kinase 3β for diabetes therapy.

Journal: Bioorganic chemistry

Published: July 04, 2025

Overcoming resistance in RET-altered cancers through rational inhibitor design and combination therapies.

Overcoming resistance in RET-altered cancers through rational inhibitor design and combination therapies.

Journal: Bioorganic chemistry

Published: May 06, 2025

Therapeutic applications and molecular mechanisms of TNIK inhibitors: A comprehensive review of current advances.

Therapeutic applications and molecular mechanisms of TNIK inhibitors: A comprehensive review of current advances.

Journal: Bioorganic chemistry

Published: April 18, 2025

A novel phosphodiesterase 4/5 dual-target inhibitor ameliorates neuroinflammation via the NF-κB and JNK pathway.

A novel phosphodiesterase 4/5 dual-target inhibitor ameliorates neuroinflammation via the NF-κB and JNK pathway.

Journal: International journal of biological macromolecules

Published: February 19, 2025

Advances of dual inhibitors based on ALK for the treatment of cancer.

Advances of dual inhibitors based on ALK for the treatment of cancer.

Journal: Bioorganic chemistry

Published: February 03, 2025

Correction: AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway.

Correction: AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway.

Journal: Cancer cell international

Published: August 03, 2024

A patent review of SCF E3 ligases inhibitors for cancer：Structural design, pharmacological activities and structure-activity relationship.

A patent review of SCF E3 ligases inhibitors for cancer：Structural design, pharmacological activities and structure-activity relationship.

Journal: European journal of medicinal chemistry

Published: June 28, 2024

Showing 1-12 of 58

Last Updated: 09/26/2026