Jianzhang T. Wu

Wenzhou, 325035, China

Last Updated: 09/26/2026

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Found 78 publications

Correction to: Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.

Correction to: Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.

Journal: Neurochemical research

Published: July 01, 2026

Discovery of novel IKKβ allosteric inhibitors as dual-antioxidant for cerebral ischemia-reperfusion injury therapy by upregulating HO-1 and SLC7A11.

Discovery of novel IKKβ allosteric inhibitors as dual-antioxidant for cerebral ischemia-reperfusion injury therapy by upregulating HO-1 and SLC7A11.

Journal: Bioorganic chemistry

Published: February 02, 2026

Engineered anchoring aptamers induce relocalization and functional inactivation of transcription factors.

Engineered anchoring aptamers induce relocalization and functional inactivation of transcription factors.

Journal: Science advances

Published: January 01, 2026

Ligand-based graph neural network, molecular dynamics and biological evaluation for identification of potential FGFR1 kinase inhibitors.

Ligand-based graph neural network, molecular dynamics and biological evaluation for identification of potential FGFR1 kinase inhibitors.

Journal: Molecular diversity

Published: September 17, 2025

Design, synthesis and anti-gastric cancer activity of stable Bisamide curcumin analogues.

Design, synthesis and anti-gastric cancer activity of stable Bisamide curcumin analogues.

Journal: Bioorganic chemistry

Published: May 14, 2025

Dimercaprol attenuates oxidative stress-induced damage of retinal ganglion cells in an in vitro and in vivo model of traumatic optic neuropathy.

Dimercaprol attenuates oxidative stress-induced damage of retinal ganglion cells in an in vitro and in vivo model of traumatic optic neuropathy.

Journal: Neuropharmacology

Published: April 10, 2025

TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition.

TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 29, 2025

Design, green synthesis, and anti-glutamate damage screening of chalcone derivatives with spiro-heterocyclic structures as potential anti-ischemic brain and eye damage agents.

Design, green synthesis, and anti-glutamate damage screening of chalcone derivatives with spiro-heterocyclic structures as potential anti-ischemic brain and eye damage agents.

Journal: Bioorganic chemistry

Published: July 11, 2024

Green synthesis of neuroprotective spirocyclic chalcone derivatives and their role in protecting against traumatic optic nerve injury.

Green synthesis of neuroprotective spirocyclic chalcone derivatives and their role in protecting against traumatic optic nerve injury.

Journal: European journal of medicinal chemistry

Published: June 15, 2024

Discovery and evaluation of novel spiroheterocyclic protective agents via a SIRT1 upregulation mechanism in cisplatin-induced premature ovarian failure.

Discovery and evaluation of novel spiroheterocyclic protective agents via a SIRT1 upregulation mechanism in cisplatin-induced premature ovarian failure.

Journal: Bioorganic & medicinal chemistry

Published: May 08, 2024

Identification of potential PIM-2 inhibitors via ligand-based generative models, molecular docking and molecular dynamics simulations.

Identification of potential PIM-2 inhibitors via ligand-based generative models, molecular docking and molecular dynamics simulations.

Journal: Molecular diversity

Published: April 01, 2024

Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer.

Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: February 22, 2024

Showing 1-12 of 78

Last Updated: 09/26/2026