Jiaofeng Chen

State Key Laboratory Of Membrane Biology
Beijing, China

Last Updated: 09/26/2026

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Found 13 publications

Diverse binding poses of agonistic neurotoxins on human Nav1.6.

Diverse binding poses of agonistic neurotoxins on human Nav1.6.

Journal: Nature
Published: June 13, 2025

Phrixotoxin-3 binds to three distinct antagonistic sites on human Nav1.6.

Phrixotoxin-3 binds to three distinct antagonistic sites on human Nav1.6.

Journal: Cell research
Published: November 29, 2024

Structural basis for human Cav3.2 inhibition by selective antagonists.

Structural basis for human Cav3.2 inhibition by selective antagonists.

Journal: Cell research
Published: December 21, 2023

Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine.

Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine.

Journal: Cell
Published: October 13, 2022

Structural basis for high-voltage activation and subtype-specific inhibition of human Nav1.8.

Structural basis for high-voltage activation and subtype-specific inhibition of human Nav1.8.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 20, 2022

Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels.

Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels.

Journal: Cell
Published: April 17, 2022

High-resolution structures of human Nav1.7 reveal gating modulation through α-π helical transition of S6IV.

High-resolution structures of human Nav1.7 reveal gating modulation through α-π helical transition of S6IV.

Journal: Cell reports
Published: December 31, 2021

An L1 retrotransposon insertion-induced deafness mouse model for studying the development and function of the cochlear stria vascularis.

An L1 retrotransposon insertion-induced deafness mouse model for studying the development and function of the cochlear stria vascularis.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 20, 2021

PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.

PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 10, 2021

Template-independent genome editing in the Pcdh15av-3j mouse, a model of human DFNB23 nonsyndromic deafness.

Template-independent genome editing in the Pcdh15av-3j mouse, a model of human DFNB23 nonsyndromic deafness.

Journal: Cell reports
Published: June 20, 2021

TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice.

TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice.

Journal: eLife
Published: April 05, 2019

Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1.

Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1.

Journal: Science (New York, N.Y.)
Published: May 22, 2018
Showing 1-12 of 13

Last Updated: 09/26/2026