Jiayu Y. Ling

Guangzhou, China

Last Updated: 09/26/2026

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Found 37 publications

Development of a Nanoscale Protein-Protein Mapping of PDE4 Interface-Disrupting Peptides.

Development of a Nanoscale Protein-Protein Mapping of PDE4 Interface-Disrupting Peptides.

Journal: Nano letters

Published: April 17, 2026

Neoadjuvant mFOLFOXIRI with or without cadonilimab versus mFOLFOX6 in locally advanced colorectal cancer: A randomized phase 2 trial (OPTICAL-2).

Neoadjuvant mFOLFOXIRI with or without cadonilimab versus mFOLFOX6 in locally advanced colorectal cancer: A randomized phase 2 trial (OPTICAL-2).

Journal: Med (New York, N.Y.)

Published: March 11, 2026

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells.

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells.

Journal: British journal of pharmacology

Published: November 09, 2025

Long-term outcomes of ripretinib versus sunitinib in Chinese patients with advanced gastrointestinal stromal tumor: An updated analysis of a phase 2 randomized clinical trial.

Long-term outcomes of ripretinib versus sunitinib in Chinese patients with advanced gastrointestinal stromal tumor: An updated analysis of a phase 2 randomized clinical trial.

Journal: Cancer

Published: April 25, 2025

TRIM29 promotes liver metastasis via enhancing hepatic colonization by stabilizing FAM83H to regulate keratin network in colorectal cancer.

TRIM29 promotes liver metastasis via enhancing hepatic colonization by stabilizing FAM83H to regulate keratin network in colorectal cancer.

Journal: Cellular signalling

Published: April 01, 2025

Targeting MDM2 homodimer and heterodimer disruption with DRx-098D in TP53 wild-type and mutant cancer cells.

Targeting MDM2 homodimer and heterodimer disruption with DRx-098D in TP53 wild-type and mutant cancer cells.

Journal: Molecular therapy. Oncology

Published: February 27, 2025

SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline.

SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline.

Journal: The international journal of biochemistry & cell biology

Published: May 07, 2024

Neoadjuvant Chemotherapy With Oxaliplatin and Fluoropyrimidine Versus Upfront Surgery for Locally Advanced Colon Cancer: The Randomized, Phase III OPTICAL Trial.

Neoadjuvant Chemotherapy With Oxaliplatin and Fluoropyrimidine Versus Upfront Surgery for Locally Advanced Colon Cancer: The Randomized, Phase III OPTICAL Trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: April 02, 2024

Disruption of the pro-oncogenic c-RAF-PDE8A complex represents a differentiated approach to treating KRAS-c-RAF dependent PDAC.

Disruption of the pro-oncogenic c-RAF-PDE8A complex represents a differentiated approach to treating KRAS-c-RAF dependent PDAC.

Journal: Scientific reports

Published: December 21, 2023

PD-1 blockade plus COX inhibitors in dMMR metastatic colorectal cancer: Clinical, genomic, and immunologic analyses from the PCOX trial.

PD-1 blockade plus COX inhibitors in dMMR metastatic colorectal cancer: Clinical, genomic, and immunologic analyses from the PCOX trial.

Journal: Med (New York, N.Y.)

Published: December 15, 2023

Capecitabine maintenance therapy in metastatic colorectal cancer patients with no evidence of disease: CAMCO trial.

Capecitabine maintenance therapy in metastatic colorectal cancer patients with no evidence of disease: CAMCO trial.

Journal: Future oncology (London, England)

Published: October 10, 2023

Analysis of the clinical characteristics and therapeutic effect of refractory juvenile dermatomyositis to tofacitinib

Analysis of the clinical characteristics and therapeutic effect of refractory juvenile dermatomyositis to tofacitinib

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics

Published: June 14, 2023

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Last Updated: 09/26/2026