Jie Ruan

Zhejiang Provincial Key Laboratory For Drug Evaluation And Clinical Research
Hangzhou, China

Last Updated: 09/26/2026

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Found 15 publications

Safety, pharmacokinetic, and pharmacodynamic characteristics of SK-08, a soluble guanylate cyclase activator, after oral administration in healthy participants: a randomized phase 1 trial.

Safety, pharmacokinetic, and pharmacodynamic characteristics of SK-08, a soluble guanylate cyclase activator, after oral administration in healthy participants: a randomized phase 1 trial.

Journal: BMC nephrology

Published: February 13, 2026

Atorvastatin alleviates atherosclerosis by improving intestinal barrier function in mice and patients by modulating inflammation.

Atorvastatin alleviates atherosclerosis by improving intestinal barrier function in mice and patients by modulating inflammation.

Journal: International immunopharmacology

Published: February 18, 2025

Efficacy and safety of Angong Niuhuang Pill in patients with acute ischemic stroke: A pilot randomized clinical trial.

Efficacy and safety of Angong Niuhuang Pill in patients with acute ischemic stroke: A pilot randomized clinical trial.

Journal: Journal of ethnopharmacology

Published: July 16, 2024

Safety, tolerability and pharmacokinetics of ASC10, a novel oral double prodrug of a broad-spectrum antiviral agent, β-d-N4-hydroxycytidine: results from a randomized, double-blind, placebo-controlled phase 1 study in Chinese healthy subjects.

Safety, tolerability and pharmacokinetics of ASC10, a novel oral double prodrug of a broad-spectrum antiviral agent, β-d-N4-hydroxycytidine: results from a randomized, double-blind, placebo-controlled phase 1 study in Chinese healthy subjects.

Journal: Expert opinion on investigational drugs

Published: July 11, 2024

A TTC19 mutation associated with progressive movement disorders and peripheral neuropathy: Case report and systematic review.

A TTC19 mutation associated with progressive movement disorders and peripheral neuropathy: Case report and systematic review.

Journal: CNS neuroscience & therapeutics

Published: April 28, 2023

Quantitative Flow Ratio-Derived Index of Microcirculatory Resistance as a Novel Tool to Identify Microcirculatory Function in Patients with Ischemia and No Obstructive Coronary Artery Disease.

Quantitative Flow Ratio-Derived Index of Microcirculatory Resistance as a Novel Tool to Identify Microcirculatory Function in Patients with Ischemia and No Obstructive Coronary Artery Disease.

Journal: Cardiology

Published: February 18, 2023

Association of Tirofiban With Functional Outcomes After Thrombectomy in Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease.

Association of Tirofiban With Functional Outcomes After Thrombectomy in Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease.

Journal: Neurology

Published: October 07, 2022

Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson's disease carrying a novel heterozygotic PARK8 (LRRK2) mutation.

Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson's disease carrying a novel heterozygotic PARK8 (LRRK2) mutation.

Journal: Stem cell research

Published: August 31, 2022

Individual treatment strategy for single urethrocutaneous fistula after hypospadias repair: a retrospective cohort study.

Individual treatment strategy for single urethrocutaneous fistula after hypospadias repair: a retrospective cohort study.

Journal: Translational andrology and urology

Published: August 08, 2022

Generation of a human iPSC line (CIBi013-A) from a patient with young-onset Parkinson's disease carrying a novel homozygous PARK7 (DJ-1) mutation.

Generation of a human iPSC line (CIBi013-A) from a patient with young-onset Parkinson's disease carrying a novel homozygous PARK7 (DJ-1) mutation.

Journal: Stem cell research

Published: June 30, 2022

Circular RNA hsa_circ_0003574 as a biomarker for prediction and diagnosis of ischemic stroke caused by intracranial atherosclerotic stenosis.

Circular RNA hsa_circ_0003574 as a biomarker for prediction and diagnosis of ischemic stroke caused by intracranial atherosclerotic stenosis.

Journal: Frontiers in pharmacology

Published: June 05, 2022

Risk factors of contrast extravasation and subsequent hemorrhagic transformation after thrombectomy.

Risk factors of contrast extravasation and subsequent hemorrhagic transformation after thrombectomy.

Journal: The Journal of international medical research

Published: October 11, 2021

Showing 1-12 of 15

Last Updated: 09/26/2026