Jimmy Lu
Edmonton, AB T6G2H7, Canada
Last Updated: 09/26/2026
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Found 10 publications
Identification of a Potent Pan-Coronaviral Main Protease Inhibitor.
Journal: Journal of medicinal chemistry
Published: July 16, 2026
Structural insights into the nirmatrelvir-resistant SARS-CoV-2 Mpro L50F/E166A/L167F triple mutant-inhibitor-complex reveal strategies for next generation coronaviral inhibitor design.
Journal: RSC medicinal chemistry
Published: April 24, 2025
Rhomboid protease GlpG regulates type 1 pili quality control and virulence in pathogenic E. coli.
Journal: Nature communications
Published: February 07, 2025
The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism.
Journal: ACS bio & med chem Au
Published: June 28, 2023
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Journal: ACS central science
Published: January 11, 2023
Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition.
Journal: Frontiers in chemistry
Published: January 11, 2022
Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors.
Journal: RSC medicinal chemistry
Published: July 22, 2021
Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability.
Journal: Journal of medicinal chemistry
Published: July 09, 2021
Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies.
Journal: European journal of medicinal chemistry
Published: March 15, 2021
N-Terminal Finger Stabilizes the S1 Pocket for the Reversible Feline Drug GC376 in the SARS-CoV-2 Mpro Dimer.
Journal: Journal of molecular biology
Published: March 01, 2021
Showing 1-10 of 10
Last Updated: 09/26/2026