Jinggen H. Liu

No. 19A Yuquan Road
Yuquan, 100049, China

Last Updated: 09/26/2026

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Found 27 publications

Discovery of a highly selective and potent kappa opioid receptor agonist from N-cyclopropylmethyl-7α-piperazinyl -6,14-endoethano-tetrahydronorthebaines.

Discovery of a highly selective and potent kappa opioid receptor agonist from N-cyclopropylmethyl-7α-piperazinyl -6,14-endoethano-tetrahydronorthebaines.

Journal: European journal of medicinal chemistry

Published: January 27, 2026

Correction to "Structure-Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6,14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists".

Correction to "Structure-Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6,14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists".

Journal: Journal of medicinal chemistry

Published: December 31, 2025

Structure-Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6,14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists.

Structure-Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6,14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists.

Journal: Journal of medicinal chemistry

Published: July 28, 2025

Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities.

Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities.

Journal: European journal of medicinal chemistry

Published: December 19, 2024

Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect.

Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect.

Journal: Journal of medicinal chemistry

Published: April 22, 2024

Modulation of Comorbid Chronic Neuropathic Pain and Anxiety-Like Behaviors by Glutamatergic Neurons in the Ventrolateral Periaqueductal Gray and the Analgesic and Anxiolytic Effects of Electroacupuncture.

Modulation of Comorbid Chronic Neuropathic Pain and Anxiety-Like Behaviors by Glutamatergic Neurons in the Ventrolateral Periaqueductal Gray and the Analgesic and Anxiolytic Effects of Electroacupuncture.

Journal: eNeuro

Published: October 31, 2023

Activation of Nrf2 antioxidant signaling alleviates gout arthritis pain and inflammation.

Activation of Nrf2 antioxidant signaling alleviates gout arthritis pain and inflammation.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: September 21, 2023

Projection-defined median raphe Pet+ subpopulations are diversely implicated in seizure.

Projection-defined median raphe Pet+ subpopulations are diversely implicated in seizure.

Journal: Neurobiology of disease

Published: August 24, 2023

A neural circuit associated with anxiety-like behaviors induced by chronic inflammatory pain and the anxiolytic effects of electroacupuncture.

A neural circuit associated with anxiety-like behaviors induced by chronic inflammatory pain and the anxiolytic effects of electroacupuncture.

Journal: CNS neuroscience & therapeutics

Published: July 21, 2023

Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone.

Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone.

Journal: European journal of medicinal chemistry

Published: May 11, 2023

Up-regulation of BDNF/TrkB signaling by δ opioid receptor agonist SNC80 modulates depressive-like behaviors in chronic restraint-stressed mice.

Up-regulation of BDNF/TrkB signaling by δ opioid receptor agonist SNC80 modulates depressive-like behaviors in chronic restraint-stressed mice.

Journal: European journal of pharmacology

Published: November 23, 2022

SLL-627 Is a Highly Selective and Potent κ Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity.

SLL-627 Is a Highly Selective and Potent κ Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity.

Journal: Journal of medicinal chemistry

Published: July 28, 2022

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Last Updated: 09/26/2026