Jinhua Zhao

No.17 South Renmin Road
Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 10 publications

Discovery of Highly Potent and Selective SOS1 Inhibitors for the Treatment of KRAS-Driven Colorectal Cancer.

Discovery of Highly Potent and Selective SOS1 Inhibitors for the Treatment of KRAS-Driven Colorectal Cancer.

Journal: Journal of medicinal chemistry

Published: June 05, 2026

Discovery of a potent and orally available SOS1 inhibitor with antitumor efficacy in KRAS-mutant colorectal cancers.

Discovery of a potent and orally available SOS1 inhibitor with antitumor efficacy in KRAS-mutant colorectal cancers.

Journal: Bioorganic chemistry

Published: February 22, 2026

A Soluble Triantennary N-Acetylgalactosamine Camptothecin Prodrug for Hepatocellular Carcinoma-Targeted Therapy.

A Soluble Triantennary N-Acetylgalactosamine Camptothecin Prodrug for Hepatocellular Carcinoma-Targeted Therapy.

Journal: Journal of medicinal chemistry

Published: July 22, 2025

Tumor-targeting nanocarriers amplified immunotherapy of cold tumors by STING activation and inhibiting immune evasion.

Tumor-targeting nanocarriers amplified immunotherapy of cold tumors by STING activation and inhibiting immune evasion.

Journal: Science advances

Published: June 27, 2025

Recent Advances in Natural Products for Cancer Immunotherapy.

Recent Advances in Natural Products for Cancer Immunotherapy.

Journal: Phytotherapy research : PTR

Published: May 07, 2025

Targeted delivery systems of siRNA based on ionizable lipid nanoparticles and cationic polymer vectors.

Targeted delivery systems of siRNA based on ionizable lipid nanoparticles and cationic polymer vectors.

Journal: Biotechnology advances

Published: September 23, 2024

Identifying TOPK and Hypoxia Hallmarks in Esophageal Tumors for Photodynamic/Chemo/Immunotherapy and Liver Metastasis Inhibition with Nanocarriers.

Identifying TOPK and Hypoxia Hallmarks in Esophageal Tumors for Photodynamic/Chemo/Immunotherapy and Liver Metastasis Inhibition with Nanocarriers.

Journal: ACS nano

Published: February 28, 2023

Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer.

Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer.

Journal: European journal of medicinal chemistry

Published: September 29, 2020

Design and SAR of Withangulatin A Analogues that Act as Covalent TrxR Inhibitors through the Michael Addition Reaction Showing Potential in Cancer Treatment.

Design and SAR of Withangulatin A Analogues that Act as Covalent TrxR Inhibitors through the Michael Addition Reaction Showing Potential in Cancer Treatment.

Journal: Journal of medicinal chemistry

Published: September 04, 2020

Charge-conversional polyethylenimine-entrapped gold nanoparticles with 131I-labeling for enhanced dual mode SPECT/CT imaging and radiotherapy of tumors.

Charge-conversional polyethylenimine-entrapped gold nanoparticles with 131I-labeling for enhanced dual mode SPECT/CT imaging and radiotherapy of tumors.

Journal: Biomaterials science

Published: June 20, 2020

Showing 1-10 of 10

Last Updated: 09/26/2026