Jinxin H. Wang

Jiangsu Key Laboratory Of Drug Design And Optimization
Nanjing, 210009, China

Last Updated: 09/26/2026

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Found 30 publications

Novel Resveratrol Derivatives as Dual PDE4 Inhibitors and Free Radical Scavengers: Rational Design, Synthesis, and Biological Evaluation.

Novel Resveratrol Derivatives as Dual PDE4 Inhibitors and Free Radical Scavengers: Rational Design, Synthesis, and Biological Evaluation.

Journal: Antioxidants (Basel, Switzerland)

Published: May 12, 2026

Discovery of Peripherally Restricted Indazole-Based Phosphodiesterase 4B Inhibitors Targeting the C-terminal Regulatory Helix for Treating Acute Lung Injury.

Discovery of Peripherally Restricted Indazole-Based Phosphodiesterase 4B Inhibitors Targeting the C-terminal Regulatory Helix for Treating Acute Lung Injury.

Journal: Journal of medicinal chemistry

Published: March 03, 2026

Targeting S1P signaling for drug development.

Targeting S1P signaling for drug development.

Journal: Drug discovery today

Published: December 14, 2025

Assessment of Tanshinone IIA Derivatives for Cardioprotection in Myocardial Ischemic Injury.

Assessment of Tanshinone IIA Derivatives for Cardioprotection in Myocardial Ischemic Injury.

Journal: Planta medica

Published: March 24, 2025

Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.

Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer.

Journal: European journal of medicinal chemistry

Published: December 21, 2024

Discovery of a Novel ASM Direct Inhibitor with a 1,5-Diphenyl-pyrazole Scaffold and Its Antidepressant Mechanism of Action.

Discovery of a Novel ASM Direct Inhibitor with a 1,5-Diphenyl-pyrazole Scaffold and Its Antidepressant Mechanism of Action.

Journal: Journal of medicinal chemistry

Published: June 18, 2024

Discovery of a novel class of reversible monoacylglycerol lipase inhibitors for potential treatment of depression.

Discovery of a novel class of reversible monoacylglycerol lipase inhibitors for potential treatment of depression.

Journal: European journal of medicinal chemistry

Published: January 10, 2024

Hybrids of selective COX-2 inhibitors and active derivatives of edaravone as COX-2 selective NSAIDs with free radical scavenging activity: Design, synthesis and biological activities.

Hybrids of selective COX-2 inhibitors and active derivatives of edaravone as COX-2 selective NSAIDs with free radical scavenging activity: Design, synthesis and biological activities.

Journal: European journal of medicinal chemistry

Published: November 29, 2023

Multiple medicinal chemistry strategies of targeting KRAS: State-of-the art and future directions.

Multiple medicinal chemistry strategies of targeting KRAS: State-of-the art and future directions.

Journal: Bioorganic chemistry

Published: September 28, 2023

Design and synthesis of a novel class of PDE4 inhibitors with antioxidant properties as bifunctional agents for the potential treatment of COPD.

Design and synthesis of a novel class of PDE4 inhibitors with antioxidant properties as bifunctional agents for the potential treatment of COPD.

Journal: European journal of medicinal chemistry

Published: February 25, 2023

Discovery of Novel N-Hydroxy-1,2,4-oxadiazole-5-formamides as ASM Direct Inhibitors for the Treatment of Atherosclerosis.

Discovery of Novel N-Hydroxy-1,2,4-oxadiazole-5-formamides as ASM Direct Inhibitors for the Treatment of Atherosclerosis.

Journal: Journal of medicinal chemistry

Published: February 14, 2023

Sappanone A: A natural PDE4 inhibitor with dual anti-inflammatory and antioxidant activities from the heartwood of Caesalpinia sappan L.

Sappanone A: A natural PDE4 inhibitor with dual anti-inflammatory and antioxidant activities from the heartwood of Caesalpinia sappan L.

Journal: Journal of ethnopharmacology

Published: September 22, 2022

Showing 1-12 of 30

Last Updated: 09/26/2026