Joachim Hochel
Leverkusen, NW, Germany
Last Updated: 09/26/2026
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Found 34 publications
Integrated Population Pharmacokinetic Analysis of Intravitreal Aflibercept Drug Products.
Journal: CPT: pharmacometrics & systems pharmacology
Published: February 19, 2026
Pharmacological principles of intravitreal drug therapy and their implications for clinical practice: a primer for the ophthalmologist.
Journal: Eye (London, England)
Published: September 09, 2025
Designing integrated early-phase protocols to reduce substantial modifications, including considerations for patient cohorts - a multi-stakeholder consensus view for a practical approach in Germany.
Journal: Frontiers in pharmacology
Published: September 05, 2025
Investigation of the Relevance of CYP3A4 Inhibition on the Pharmacokinetics of the Novel P2X3 Antagonist Filapixant: Results of In Vitro Explorations and a Fixed-Sequence Clinical Trial with Itraconazole in Healthy Volunteers.
Journal: International journal of molecular sciences
Published: August 18, 2025
Establishing a Quantitative Framework for Combined Oral Contraceptives: Evaluating the Impact of Drug-Drug Interactions on Exposure and Clinical (Surrogate) Efficacy Endpoints.
Journal: Journal of clinical pharmacology
Published: April 07, 2025
Zabedosertib, a novel interleukin-1 receptor-associated kinase-4 inhibitor, shows a favorable pharmacokinetic and safety profile across multiple phase 1 studies.
Journal: Frontiers in pharmacology
Published: November 01, 2024
Development of breakthrough bleeding model of combined-oral contraceptives utilizing model-based meta-analysis.
Journal: CPT: pharmacometrics & systems pharmacology
Published: June 21, 2024
Correction: Systemic exposure to aflibercept after intravitreal injection in premature neonates with retinopathy of prematurity: results from the FIREFLEYE randomized phase 3 study.
Journal: Eye (London, England)
Published: February 09, 2024
Systemic exposure to aflibercept after intravitreal injection in premature neonates with retinopathy of prematurity: results from the FIREFLEYE randomized phase 3 study.
Journal: Eye (London, England)
Published: October 16, 2023
Development of a Translational Exposure-Bracketing Approach to Streamline the Development of Hormonal Contraceptive Drug Products.
Journal: Clinical pharmacology and therapeutics
Published: February 15, 2022
Metabolism in the Gastrointestinal Tract: Relevance for Drug Development.
Journal: Drug research
Published: November 17, 2021
Clinical Pharmacokinetics and Pharmacodynamics of the Selective Progesterone Receptor Modulator Vilaprisan: A Comprehensive Overview.
Journal: Clinical pharmacokinetics
Published: August 27, 2021
Last Updated: 09/26/2026