Joanna P. Nicholls
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 12 publications
RNA activation as a precision dosing modality: MTL-CEBPA for controlled enzyme elevation in MPS I-H.
RNA activation as a precision dosing modality: MTL-CEBPA for controlled enzyme elevation in MPS I-H.
Journal: Frontiers in medicine
Published: February 18, 2026
GalNAc-conjugated siRNA targeting C/EBPβ reverses metabolic dysfunction and restores liver homeostasis in a murine MASLD model.
Journal: Molecular therapy. Nucleic acids
Published: October 23, 2025
TIMEPOINT, a phase 1 study combining MTL-CEBPA with pembrolizumab, supports the immunomodulatory effect of MTL-CEBPA in solid tumors.
Journal: Cell reports. Medicine
Published: November 16, 2023
RNA Activation-A Novel Approach to Therapeutically Upregulate Gene Transcription.
Journal: Molecules (Basel, Switzerland)
Published: September 30, 2021
MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: January 31, 2020
Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.
Journal: Molecular therapy. Nucleic acids
Published: May 22, 2019
Intra-Arterial Immunoselected CD34+ Stem Cells for Acute Ischemic Stroke.
Journal: Stem cells translational medicine
Published: August 10, 2014
A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells.
Journal: Molecular therapy. Nucleic acids
Published: June 06, 2013
Exploiting human CD34+ stem cell-conditioned medium for tissue repair.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: May 03, 2013
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo.
Journal: Hepatology (Baltimore, Md.)
Published: March 06, 2013
MicroRNA-181a* Targets Nanog in a Subpopulation of CD34(+) Cells Isolated From Peripheral Blood.
Journal: Molecular therapy. Nucleic acids
Published: January 25, 2013
A perspective on non-catalytic Src homology (SH) adaptor signalling proteins.
Journal: Cellular signalling
Published: September 30, 2011
Showing 1-12 of 12
Last Updated: 09/26/2026