Joaquin Castilla

Bilbao, PV 48009, Spain

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 88 publications

Exploring PrPC unfolding as a critical step preceding its refolding in the context of PrPSc propagation.

Exploring PrPC unfolding as a critical step preceding its refolding in the context of PrPSc propagation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 29, 2026

The axonal transport velocity of prions is independent of prion formation.

The axonal transport velocity of prions is independent of prion formation.

Journal: PLoS pathogens

Published: March 01, 2026

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy.

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy.

Journal: bioRxiv : the preprint server for biology

Published: February 27, 2026

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy.

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy.

Journal: Neurobiology of disease

Published: February 17, 2026

Transmission Ratio Distortion in Genetic Prion Diseases: Clarifying Methodological Considerations.

Transmission Ratio Distortion in Genetic Prion Diseases: Clarifying Methodological Considerations.

Journal: European journal of neurology

Published: January 28, 2026

Rapid generation of prion disease models using AAV-delivered PrP variants in knockout mice.

Rapid generation of prion disease models using AAV-delivered PrP variants in knockout mice.

Journal: Brain pathology (Zurich, Switzerland)

Published: December 01, 2025

Variably Protease-Sensitive Prionopathy: Two New Cases With Motor Neuron-Dementia Syndrome.

Variably Protease-Sensitive Prionopathy: Two New Cases With Motor Neuron-Dementia Syndrome.

Journal: Annals of clinical and translational neurology

Published: October 31, 2025

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains.

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains.

Journal: Brain pathology (Zurich, Switzerland)

Published: September 09, 2025

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness.

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness.

Journal: Acta neuropathologica communications

Published: August 26, 2025

The Risk of Transmission of Genetic Prion Diseases is Greater Than 50.

The Risk of Transmission of Genetic Prion Diseases is Greater Than 50.

Journal: European journal of neurology

Published: August 05, 2025

Advancing prion diagnostics: full-length human E200K RT-QuIC substrate facilitates prion detection in tear fluid and improves sensitivity in cerebrospinal fluid.

Advancing prion diagnostics: full-length human E200K RT-QuIC substrate facilitates prion detection in tear fluid and improves sensitivity in cerebrospinal fluid.

Journal: Acta neuropathologica communications

Published: July 25, 2025

D178N prion protein mutation endows RML prions with new strain properties that do not mimic human genetic prion diseases.

D178N prion protein mutation endows RML prions with new strain properties that do not mimic human genetic prion diseases.

Journal: Acta neuropathologica

Published: July 22, 2025

Showing 1-12 of 88

Last Updated: 09/26/2026