Joaquin J. Pastor

Almagro, MD 28029, Spain

Last Updated: 09/26/2026

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Found 38 publications

SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.

SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.

Journal: Cell death & disease

Published: July 05, 2024

Underutilized Crocus Sativus L. Flowers: A Hidden Source of Sustainable High Value-Added Ingredients.

Underutilized Crocus Sativus L. Flowers: A Hidden Source of Sustainable High Value-Added Ingredients.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands)

Published: April 10, 2023

mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity.

mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity.

Journal: Molecules (Basel, Switzerland)

Published: July 20, 2022

Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors.

Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors.

Journal: ACS medicinal chemistry letters

Published: July 28, 2021

Corrigendum to <' Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors' [Eur. J. Med. Chem. 211 (2021), 113109].

Corrigendum to <' Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors' [Eur. J. Med. Chem. 211 (2021), 113109].

Journal: European journal of medicinal chemistry

Published: July 20, 2021

A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.

A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.

Journal: EMBO molecular medicine

Published: May 14, 2021

Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3.

Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences

Published: April 26, 2021

Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors.

Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors.

Journal: European journal of medicinal chemistry

Published: September 11, 2020

Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells.

Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells.

Journal: Cancers

Published: June 21, 2020

Pyrido[2,3-b][1,5]benzoxazepin-5(6H)-one derivatives as CDK8 inhibitors.

Pyrido[2,3-b][1,5]benzoxazepin-5(6H)-one derivatives as CDK8 inhibitors.

Journal: European journal of medicinal chemistry

Published: March 11, 2020

Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma.

Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma.

Journal: EMBO molecular medicine

Published: January 10, 2020

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.

Journal: Nature cell biology

Published: May 02, 2019

Showing 1-12 of 38

Last Updated: 09/26/2026