Johann J. Leban

Salzburg, 5020, Austria

Last Updated: 09/26/2026

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Found 25 publications

Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry.

Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry.

Journal: Biomolecules
Published: July 07, 2023

Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat.

Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat.

Journal: Biomolecules
Published: January 11, 2023

The Novel Analogue of Modafinil CE-158 Protects Social Memory against Interference and Triggers the Release of Dopamine in the Nucleus Accumbens of Mice.

The Novel Analogue of Modafinil CE-158 Protects Social Memory against Interference and Triggers the Release of Dopamine in the Nucleus Accumbens of Mice.

Journal: Biomolecules
Published: February 03, 2022

Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition.

Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition.

Journal: Molecular psychiatry
Published: July 10, 2021

Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.

Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.

Journal: Journal of medicinal chemistry
Published: December 17, 2019

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

Journal: Journal of medicinal chemistry
Published: April 10, 2018

A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval.

A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval.

Journal: Behavioural brain research
Published: December 12, 2017

Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors.

Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors.

Journal: Journal of medicinal chemistry
Published: November 02, 2017

A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.

A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.

Journal: Behavioural brain research
Published: May 23, 2017

Inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) exert a strong anti-herpesviral activity.

Inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) exert a strong anti-herpesviral activity.

Journal: Antiviral research
Published: December 15, 2016

A novel heterocyclic compound targeting the dopamine transporter improves performance in the radial arm maze and modulates dopamine receptors D1-D3.

A novel heterocyclic compound targeting the dopamine transporter improves performance in the radial arm maze and modulates dopamine receptors D1-D3.

Journal: Behavioural brain research
Published: May 27, 2016

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.

Journal: Oncotarget
Published: December 23, 2015
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Last Updated: 09/26/2026