Johanna Huchting

Hamburg, HH 22525, Germany

Last Updated: 09/26/2026

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Found 11 publications

From library to landscape: integrative annotation workflows for compound libraries in drug repurposing.

From library to landscape: integrative annotation workflows for compound libraries in drug repurposing.

Journal: Database : the journal of biological databases and curation
Published: August 13, 2025

Experimental and machine learning-based exploration of repurposed drugs reveals chemical features underlying phospholipidosis.

Experimental and machine learning-based exploration of repurposed drugs reveals chemical features underlying phospholipidosis.

Journal: Patterns (New York, N.Y.)
Published: June 18, 2025

Optimization and Evaluation of Complementary Degrader Discovery Assays for Application in Screening.

Optimization and Evaluation of Complementary Degrader Discovery Assays for Application in Screening.

Journal: ACS pharmacology & translational science
Published: March 16, 2025

T-705-Derived Prodrugs Show High Antiviral Efficacies against a Broad Range of Influenza A Viruses with Synergistic Effects When Combined with Oseltamivir.

T-705-Derived Prodrugs Show High Antiviral Efficacies against a Broad Range of Influenza A Viruses with Synergistic Effects When Combined with Oseltamivir.

Journal: Pharmaceutics
Published: April 23, 2023

Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.

Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.

Journal: Cell reports
Published: May 31, 2022

Targeting viral genome synthesis as broad-spectrum approach against RNA virus infections.

Targeting viral genome synthesis as broad-spectrum approach against RNA virus infections.

Journal: Antiviral chemistry & chemotherapy
Published: December 10, 2020

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis.

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis.

Journal: Nature communications
Published: June 25, 2020

Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase.

Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase.

Journal: bioRxiv : the preprint server for biology
Published: June 09, 2020

Cell line-dependent activation and antiviral activity of T-1105, the non-fluorinated analogue of T-705 (favipiravir).

Cell line-dependent activation and antiviral activity of T-1105, the non-fluorinated analogue of T-705 (favipiravir).

Journal: Antiviral research
Published: March 05, 2019

Prodrugs of the Phosphoribosylated Forms of Hydroxypyrazinecarboxamide Pseudobase T-705 and Its De-Fluoro Analogue T-1105 as Potent Influenza Virus Inhibitors.

Prodrugs of the Phosphoribosylated Forms of Hydroxypyrazinecarboxamide Pseudobase T-705 and Its De-Fluoro Analogue T-1105 as Potent Influenza Virus Inhibitors.

Journal: Journal of medicinal chemistry
Published: June 16, 2018

Synthesis of T-705-Ribonucleoside and T-705-Ribonucleotide and Studies of Chemical Stability.

Synthesis of T-705-Ribonucleoside and T-705-Ribonucleotide and Studies of Chemical Stability.

Journal: ChemMedChem
Published: February 20, 2017
Showing 1-11 of 11

Last Updated: 09/26/2026