Johanna I. Kiiski

Helsinki, Finland

Last Updated: 09/26/2026

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Found 36 publications

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure.

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure.

Journal: Clinical pharmacology and therapeutics

Published: November 29, 2025

Capillary Sampling Enables Venetoclax Concentration Measurement in Acute Myeloid Leukaemia Within Academic Multicentre Trial.

Capillary Sampling Enables Venetoclax Concentration Measurement in Acute Myeloid Leukaemia Within Academic Multicentre Trial.

Journal: Basic & clinical pharmacology & toxicology

Published: November 18, 2024

A Phenotyping Tool for Seven Cytochrome P450 Enzymes and Two Transporters: Application to Examine the Effects of Clopidogrel and Gemfibrozil.

A Phenotyping Tool for Seven Cytochrome P450 Enzymes and Two Transporters: Application to Examine the Effects of Clopidogrel and Gemfibrozil.

Journal: Clinical pharmacology and therapeutics

Published: November 14, 2024

Genetic and Functional Characterization of DPYD Exon 4 Deletion Common in the Finnish Population.

Genetic and Functional Characterization of DPYD Exon 4 Deletion Common in the Finnish Population.

Journal: Basic & clinical pharmacology & toxicology

Published: October 10, 2024

Population Pharmacokinetic Quantification of CYP2D6 Activity in Codeine Metabolism in Ambulatory Surgical Patients for Model-Informed Precision Dosing.

Population Pharmacokinetic Quantification of CYP2D6 Activity in Codeine Metabolism in Ambulatory Surgical Patients for Model-Informed Precision Dosing.

Journal: Clinical pharmacokinetics

Published: September 30, 2024

Does cytochrome 2D6 genotype affect the analgesic efficacy of codeine after ambulatory surgery? Prospective trial in 987 adults.

Does cytochrome 2D6 genotype affect the analgesic efficacy of codeine after ambulatory surgery? Prospective trial in 987 adults.

Journal: Acta anaesthesiologica Scandinavica

Published: May 22, 2024

Solanidine is a sensitive and specific dietary biomarker for CYP2D6 activity.

Solanidine is a sensitive and specific dietary biomarker for CYP2D6 activity.

Journal: Human genomics

Published: November 02, 2023

Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin.

Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin.

Journal: Clinical pharmacology and therapeutics

Published: August 04, 2023

Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2 , and CYP2C9 variants.

Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2 , and CYP2C9 variants.

Journal: Pharmacogenetics and genomics

Published: July 25, 2023

NTHL1 is a recessive cancer susceptibility gene.

NTHL1 is a recessive cancer susceptibility gene.

Journal: Scientific reports

Published: July 06, 2023

CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel.

CYP2C19 loss-of-function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel.

Journal: Clinical and translational science

Published: June 12, 2023

Posaconazole-ibrutinib interaction cannot be avoided by staggered dosing: How to optimize ibrutinib dose during posaconazole treatment.

Posaconazole-ibrutinib interaction cannot be avoided by staggered dosing: How to optimize ibrutinib dose during posaconazole treatment.

Journal: British journal of clinical pharmacology

Published: May 21, 2023

Showing 1-12 of 36

Last Updated: 09/26/2026