Johannes Kuehle

Koeln, NW 50931, Germany

Last Updated: 09/26/2026

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Found 18 publications

CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process.

CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process.

Journal: Cancer gene therapy

Published: March 08, 2023

Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy.

Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy.

Journal: Cells

Published: March 01, 2022

Generation of an NFκB-Driven Alpharetroviral "All-in-One" Vector Construct as a Potent Tool for CAR NK Cell Therapy.

Generation of an NFκB-Driven Alpharetroviral "All-in-One" Vector Construct as a Potent Tool for CAR NK Cell Therapy.

Journal: Frontiers in immunology

Published: July 31, 2021

Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages.

Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages.

Journal: Journal of personalized medicine

Published: February 08, 2021

PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model.

PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model.

Journal: Molecular therapy oncolytics

Published: March 04, 2020

Design and Characterization of an "All-in-One" Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines.

Design and Characterization of an "All-in-One" Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines.

Journal: Cancers

Published: December 06, 2019

Lentiviral gene therapy and vitamin B3 treatment enable granulocytic differentiation of G6PC3-deficient induced pluripotent stem cells.

Lentiviral gene therapy and vitamin B3 treatment enable granulocytic differentiation of G6PC3-deficient induced pluripotent stem cells.

Journal: Gene therapy

Published: August 07, 2019

FimH-based display of functional eukaryotic proteins on bacteria surfaces.

FimH-based display of functional eukaryotic proteins on bacteria surfaces.

Journal: Scientific reports

Published: March 04, 2019

Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout.

Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout.

Journal: Molecular therapy. Nucleic acids

Published: April 06, 2018

CD28-ζ CAR T Cells Resist TGF-β Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop.

CD28-ζ CAR T Cells Resist TGF-β Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: January 24, 2018

Correction to: Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells.

Correction to: Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells.

Journal: Retrovirology

Published: October 20, 2017

Genetic Modification of T Cells with Chimeric Antigen Receptors: A Laboratory Manual.

Genetic Modification of T Cells with Chimeric Antigen Receptors: A Laboratory Manual.

Journal: Human gene therapy methods

Published: July 26, 2017

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Last Updated: 09/26/2026