Johannes Lengler

Baxalta Innovations GmbH, Donau City Str. 7
Vienna, 1220, Austria

Last Updated: 09/26/2026

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Found 20 publications

Stable Boundaries of Opinion Dynamics in Heterogeneous Spatial Complex Networks.

Stable Boundaries of Opinion Dynamics in Heterogeneous Spatial Complex Networks.

Journal: Entropy (Basel, Switzerland)

Published: March 09, 2026

Potency by design: Novel insights in transfection and purification for manufacturing of rAAV gene therapy vectors.

Potency by design: Novel insights in transfection and purification for manufacturing of rAAV gene therapy vectors.

Journal: Journal of biotechnology

Published: September 29, 2024

Preclinical development of TAK-754, a high-performance AAV8-based vector expressing coagulation factor VIII.

Preclinical development of TAK-754, a high-performance AAV8-based vector expressing coagulation factor VIII.

Journal: Molecular therapy. Methods & clinical development

Published: August 30, 2024

Cas-CLOVER-mediated knockout of STAT1: A novel approach to engineer packaging HEK-293 cell lines used for rAAV production.

Cas-CLOVER-mediated knockout of STAT1: A novel approach to engineer packaging HEK-293 cell lines used for rAAV production.

Journal: Biotechnology journal

Published: July 05, 2024

Crucial aspects for maintaining rAAV stability.

Crucial aspects for maintaining rAAV stability.

Journal: Scientific reports

Published: July 04, 2024

Orthogonal characterization of rAAV9 reveals unexpected transgene heterogeneity.

Orthogonal characterization of rAAV9 reveals unexpected transgene heterogeneity.

Journal: Journal of biotechnology

Published: June 06, 2024

OneMax Is Not the Easiest Function for Fitness Improvements.

OneMax Is Not the Easiest Function for Fitness Improvements.

Journal: Evolutionary computation

Published: March 17, 2023

Assessment of the percentage of full recombinant adeno-associated virus particles in a gene therapy drug using CryoTEM.

Assessment of the percentage of full recombinant adeno-associated virus particles in a gene therapy drug using CryoTEM.

Journal: PloS one

Published: December 22, 2021

Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency.

Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency.

Journal: Molecular therapy. Methods & clinical development

Published: August 18, 2020

Development of an In Vitro Biopotency Assay for an AAV8 Hemophilia B Gene Therapy Vector Suitable for Clinical Product Release.

Development of an In Vitro Biopotency Assay for an AAV8 Hemophilia B Gene Therapy Vector Suitable for Clinical Product Release.

Journal: Molecular therapy. Methods & clinical development

Published: February 19, 2020

A Hippocampal Model for Behavioral Time Acquisition and Fast Bidirectional Replay of Spatio-Temporal Memory Sequences.

A Hippocampal Model for Behavioral Time Acquisition and Fast Bidirectional Replay of Spatio-Temporal Memory Sequences.

Journal: Frontiers in neuroscience

Published: August 17, 2018

On the origin of lognormal network synchrony in CA1.

On the origin of lognormal network synchrony in CA1.

Journal: Hippocampus

Published: February 27, 2018

Showing 1-12 of 20

Last Updated: 09/26/2026