Johannes M. Van Den Boom-Van Den Broek
Essen, NW, Germany
Last Updated: 09/26/2026
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Found 28 publications
Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97Ufd1-Npl4 complex.
Journal: Life science alliance
Published: March 16, 2026
The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding.
Journal: Science advances
Published: March 06, 2026
Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatases.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 29, 2024
ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains.
Journal: The EMBO journal
Published: August 26, 2024
Impact of lifestyle risk factors on atrial fibrillation: Mechanisms and prevention approaches - A narrative review.
Journal: International journal of cardiology. Cardiovascular risk and prevention
Published: August 01, 2024
Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH.
Journal: Molecular cell
Published: October 25, 2023
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.
Journal: Nature communications
Published: July 20, 2023
Targeting of client proteins to the VCP/p97/Cdc48 unfolding machine.
Journal: Frontiers in molecular biosciences
Published: January 12, 2023
Structural basis of ubiquitin-independent PP1 complex disassembly by p97.
Journal: The EMBO journal
Published: November 21, 2022
Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTN.
Journal: The Journal of biological chemistry
Published: March 03, 2022
The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase.
Journal: Nature communications
Published: February 25, 2022
Last Updated: 09/26/2026