Johannes Sam

Schlieren, ZH, Switzerland

Last Updated: 09/26/2026

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Found 33 publications

Precision modeling of tumor antigen-specific T-cell responses in humanized mice for preclinical assessment of cancer immunotherapies.

Precision modeling of tumor antigen-specific T-cell responses in humanized mice for preclinical assessment of cancer immunotherapies.

Journal: Journal for immunotherapy of cancer

Published: March 27, 2026

Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs.

Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs.

Journal: Veterinary pathology

Published: March 05, 2026

P329G-engager: a universal mix & match antibody-based adaptor platform for cancer immunotherapy.

P329G-engager: a universal mix & match antibody-based adaptor platform for cancer immunotherapy.

Journal: mAbs

Published: December 16, 2025

Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs.

Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs.

Journal: mAbs

Published: November 06, 2025

CEA-4-1BBL: CEACAM5-Targeted 4-1BB Ligand Fusion Proteins for Cis Co-Stimulation with CEA-TCB.

CEA-4-1BBL: CEACAM5-Targeted 4-1BB Ligand Fusion Proteins for Cis Co-Stimulation with CEA-TCB.

Journal: Antibodies (Basel, Switzerland)

Published: September 27, 2025

Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow.

Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 16, 2025

Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies.

Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies.

Journal: Oncoimmunology

Published: September 02, 2025

Molecular Features of Response and Resistance to Glofitamab, a T-Cell Engager for treatment of Large B-Cell Lymphoma.

Molecular Features of Response and Resistance to Glofitamab, a T-Cell Engager for treatment of Large B-Cell Lymphoma.

Journal: Blood advances

Published: April 21, 2025

Molecular features of response and resistance to glofitamab, a T-cell engager for treatment of large B-cell lymphoma.

Molecular features of response and resistance to glofitamab, a T-cell engager for treatment of large B-cell lymphoma.

Journal: Blood advances

Published: April 21, 2025

Preclinical advances in glofitamab combinations: a new frontier for non-Hodgkin lymphoma.

Preclinical advances in glofitamab combinations: a new frontier for non-Hodgkin lymphoma.

Journal: Blood

Published: February 20, 2025

CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.

CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.

Journal: Blood

Published: November 27, 2023

Dissecting the Mechanisms Underlying the Cytokine Release Syndrome (CRS) Mediated by T-Cell Bispecific Antibodies.

Dissecting the Mechanisms Underlying the Cytokine Release Syndrome (CRS) Mediated by T-Cell Bispecific Antibodies.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: December 02, 2022

Showing 1-12 of 33

Last Updated: 09/26/2026