John C. Alexander
London, ENG SW36JB, United Kingdom
Last Updated: 09/26/2026
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Found 26 publications
Proteogenomic discovery of RB1-defective phenocopy in cancer predicts disease outcome, response to treatment, and therapeutic targets.
Journal: Science advances
Published: March 26, 2025
PPP2R1A mutations cause ATR inhibitor sensitivity in ovarian clear cell carcinoma.
Journal: Oncogene
Published: June 17, 2024
The transcriptomic architecture of common cancers reflects synthetic lethal interactions.
Journal: Nature genetics
Published: April 18, 2024
The identification of functional regions of MEK1 using CRISPR tiling screens.
Journal: Communications biology
Published: December 14, 2023
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer.
Journal: British journal of cancer
Published: June 02, 2023
Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
Journal: Molecular oncology
Published: May 11, 2023
Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers.
Journal: Cancer research
Published: February 27, 2023
MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells.
Journal: Cell reports
Published: September 02, 2022
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance.
Journal: Cancer research
Published: December 21, 2021
ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype.
Journal: International journal of molecular sciences
Published: August 24, 2021
Last Updated: 09/26/2026