John C. Whittaker

Target Sciences R&D
Stevenage, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 56 publications

Adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics.

Adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics.

Journal: Clinical trials (London, England)

Published: August 04, 2026

Adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics.

Adaptive versus fixed designs in confirmatory clinical trials: centering the choice on ethics.

Journal: Clinical trials (London, England)

Published: August 04, 2026

A genomic-led strategy to anticipate drug safety effects.

A genomic-led strategy to anticipate drug safety effects.

Journal: PLoS genetics

Published: September 30, 2025

Leveraging large-scale biobanks for therapeutic target discovery.

Leveraging large-scale biobanks for therapeutic target discovery.

Journal: HGG advances

Published: April 17, 2025

A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank.

A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank.

Journal: Scientific reports

Published: April 14, 2025

Human genetics suggests differing causal pathways from HMGCR inhibition to coronary artery disease and type 2 diabetes.

Human genetics suggests differing causal pathways from HMGCR inhibition to coronary artery disease and type 2 diabetes.

Journal: International journal of epidemiology

Published: December 20, 2024

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Journal: Nature genetics

Published: April 19, 2024

Using genetic association data to guide drug discovery and development: Review of methods and applications.

Using genetic association data to guide drug discovery and development: Review of methods and applications.

Journal: American journal of human genetics

Published: February 03, 2023

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure.

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure.

Journal: Nature communications

Published: December 08, 2022

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic.

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic.

Journal: The Journal of experimental medicine

Published: December 05, 2021

A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma.

A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma.

Journal: BMC cancer

Published: April 27, 2021

Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.

Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: January 21, 2021

Showing 1-12 of 56

Last Updated: 09/26/2026