John D. Chan
900 Saint Denis Street
Montreal, QC H2X0A9, Canada
Montreal, QC H2X0A9, Canada
Last Updated: 09/26/2026
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Found 34 publications
Intrarenal renin-angiotensin system inactivation ameliorates tubulopathy via attenuation of mitochondrial oxidative stress, dysfunction and senescence in diabetes.
Journal: Clinical science (London, England : 1979)
Published: September 15, 2025
Intrarenal Renin-Angiotensin System Inactivation Ameliorates Tubulopathy via Attenuation of Mitochondrial Oxidative Stress, Dysfunction and Senescence in Diabetes.
Journal: Clinical science (London, England : 1979)
Published: September 15, 2025
Dapagliflozin, in addition to ramipril, ameliorates kidney disease progression in mice with Alport syndrome.
Journal: American journal of physiology. Renal physiology
Published: June 11, 2025
Canagliflozin inhibits hedgehog interacting protein (Hhip) induction of tubulopathy in diabetic Akita mice.
Journal: Translational research : the journal of laboratory and clinical medicine
Published: July 24, 2024
Renal Tubule-Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes.
Journal: Diabetes
Published: July 03, 2024
Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.
Journal: Translational research : the journal of laboratory and clinical medicine
Published: August 11, 2023
NRF2 Deficiency Attenuates Diabetic Kidney Disease in Db/Db Mice via Down-Regulation of Angiotensinogen, SGLT2, CD36, and FABP4 Expression and Lipid Accumulation in Renal Proximal Tubular Cells.
Journal: Antioxidants (Basel, Switzerland)
Published: June 30, 2023
Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit.
Journal: Canadian journal of kidney health and disease
Published: July 14, 2022
Hedgehog interacting protein activates sodium-glucose cotransporter 2 expression and promotes renal tubular epithelial cell senescence in a mouse model of type 1 diabetes.
Journal: Diabetologia
Published: April 14, 2022
Angiotensin II type-2-receptor stimulation ameliorates focal and segmental glomerulosclerosis in mice.
Journal: Clinical science (London, England : 1979)
Published: March 21, 2022
Deletion of heterogeneous nuclear ribonucleoprotein F in renal tubules downregulates SGLT2 expression and attenuates hyperfiltration and kidney injury in a mouse model of diabetes.
Journal: Diabetologia
Published: February 11, 2021
Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice.
Journal: Clinical science (London, England : 1979)
Published: January 28, 2021
Last Updated: 09/26/2026