John D. Hayes

James Arrott Drive
Dundee, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 49 publications

The electrophilic metabolite of kynurenine, kynurenine-CKA, targets C151 in Keap1 to derepress Nrf2.

The electrophilic metabolite of kynurenine, kynurenine-CKA, targets C151 in Keap1 to derepress Nrf2.

Journal: bioRxiv : the preprint server for biology

Published: December 03, 2025

The CNC-bZIP transcription factor Nrf2 controls expression of matrix metalloproteases in murine macrophages.

The CNC-bZIP transcription factor Nrf2 controls expression of matrix metalloproteases in murine macrophages.

Journal: Journal of leukocyte biology

Published: October 14, 2025

The electrophilic metabolite of kynurenine, kynurenine-CKA, requires C151 in Keap1 to derepress Nrf2.

The electrophilic metabolite of kynurenine, kynurenine-CKA, requires C151 in Keap1 to derepress Nrf2.

Journal: Redox biology

Published: October 01, 2025

Genetic Deletion of RHAMM Alleviates Hepatic Oxidative Stress, Reversing Thyroid Stimulating Hormone Elevation in Male Obese Mice.

Genetic Deletion of RHAMM Alleviates Hepatic Oxidative Stress, Reversing Thyroid Stimulating Hormone Elevation in Male Obese Mice.

Journal: Cells

Published: August 14, 2025

Far infrared therapy improves vascular function by enhancing endothelial function and decreasing arterial stiffness via cytoprotective pathways.

Far infrared therapy improves vascular function by enhancing endothelial function and decreasing arterial stiffness via cytoprotective pathways.

Journal: Free radical biology & medicine

Published: July 19, 2025

Dual targeting of Keap1 and Gsk-3 by hexaraphane in the regulation of transcription factor Nrf2.

Dual targeting of Keap1 and Gsk-3 by hexaraphane in the regulation of transcription factor Nrf2.

Journal: Free radical biology & medicine

Published: June 30, 2025

CD5L is a target of transcription factor Nrf2.

CD5L is a target of transcription factor Nrf2.

Journal: Biochemical and biophysical research communications

Published: May 22, 2025

Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases.

Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases.

Journal: Redox biology

Published: December 21, 2024

Regulating Nrf2 activity: ubiquitin ligases and signaling molecules in redox homeostasis.

Regulating Nrf2 activity: ubiquitin ligases and signaling molecules in redox homeostasis.

Journal: Trends in biochemical sciences

Published: September 18, 2024

Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells.

Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells.

Journal: Redox biology

Published: January 11, 2024

Corrigendum to "An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver" [Redox Biol. 55 (2022) 102396/PMID: 35839629].

Corrigendum to "An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver" [Redox Biol. 55 (2022) 102396/PMID: 35839629].

Journal: Redox biology

Published: August 05, 2022

Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2.

Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2.

Journal: Free radical biology & medicine

Published: June 08, 2022

Showing 1-12 of 49

Last Updated: 09/26/2026