John D. O'neil - Publications

Lipopolysaccharide induces HIF-1α accumulation via MAPK p38-mediated mRNA stabilization and dexamethasone-sensitive protein stabilization.

Journal: The Journal of biological chemistry

Published: May 14, 2025

Fibroblasts Derived From Vestibular Schwannoma Express Protumorogenic Markers.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Published: September 21, 2023

The glucocorticoid dexamethasone inhibits HIF-1α stabilization and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages.

Journal: Discovery immunology

Published: September 08, 2023

Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β.

Journal: Frontiers in immunology

Published: March 20, 2023

Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48.

Journal: Science advances

Published: December 08, 2021

The Epstein-Barr Virus-Encoded EBNA1 Protein Activates the Bone Morphogenic Protein (BMP) Signalling Pathway to Promote Carcinoma Cell Migration.

Journal: Pathogens (Basel, Switzerland)

Published: June 20, 2020

Evaluation of full-length nanopore 16S sequencing for detection of pathogens in microbial keratitis.

Journal: PeerJ

Published: May 04, 2020

MAPK p38 regulates inflammatory gene expression via tristetraprolin: Doing good by stealth.

Journal: The international journal of biochemistry & cell biology

Published: May 10, 2017

Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin.

Journal: Scientific reports

Published: January 17, 2017

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Journal: The Journal of biological chemistry

Published: December 17, 2016

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.

Journal: Molecular and cellular biology

Published: September 30, 2016

Priming in response to pro-inflammatory cytokines is a feature of adult synovial but not dermal fibroblasts.

Journal: Arthritis research & therapy

Published: July 20, 2016