John F. Macdonald

London, ON N6A5B7, Canada

Last Updated: 09/26/2026

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Found 13 publications

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit.

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit.

Journal: Scientific reports

Published: August 25, 2016

The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.

The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: November 13, 2015

Differential regulation of NMDAR and NMDAR-mediated metaplasticity by anandamide and 2-AG in the hippocampus.

Differential regulation of NMDAR and NMDAR-mediated metaplasticity by anandamide and 2-AG in the hippocampus.

Journal: Hippocampus

Published: July 28, 2014

Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs).

Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs).

Journal: International journal of molecular sciences

Published: November 26, 2013

The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity.

The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: October 18, 2013

Interaction of acetylcholinesterase with neurexin-1β regulates glutamatergic synaptic stability in hippocampal neurons.

Interaction of acetylcholinesterase with neurexin-1β regulates glutamatergic synaptic stability in hippocampal neurons.

Journal: Molecular brain

Published: October 13, 2013

Optogenetics and synaptic plasticity.

Optogenetics and synaptic plasticity.

Journal: Acta pharmacologica Sinica

Published: July 10, 2013

Isoflurane regulates atypical type-A γ-aminobutyric acid receptors in alveolar type II epithelial cells.

Isoflurane regulates atypical type-A γ-aminobutyric acid receptors in alveolar type II epithelial cells.

Journal: Anesthesiology

Published: March 15, 2013

Nonselective cation channels and links to hippocampal ischemia, aging, and dementia.

Nonselective cation channels and links to hippocampal ischemia, aging, and dementia.

Journal: Advances in experimental medicine and biology

Published: December 11, 2012

Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation.

Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 10, 2012

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.

Journal: Molecular brain

Published: January 13, 2012

Calcium-mediated paired pulse depression in juvenile rat dorsal striatum.

Calcium-mediated paired pulse depression in juvenile rat dorsal striatum.

Journal: Neural regeneration research

Published: November 18, 2011

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Last Updated: 09/26/2026