John F. Diffley

John F. Diffley

London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 68 publications

Publisher Correction: Targeting cancer-specific mutations with RNA-triggered chromatin shredding.

Publisher Correction: Targeting cancer-specific mutations with RNA-triggered chromatin shredding.

Journal: Nature
Published: August 14, 2026

Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding.

Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding.

Journal: bioRxiv : the preprint server for biology
Published: May 18, 2026

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding.

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding.

Journal: Nature
Published: November 04, 2025

Structure of the pre-initiation complex explains CMGE biogenesis.

Structure of the pre-initiation complex explains CMGE biogenesis.

Journal: Nature
Published: July 07, 2025

Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication.

Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication.

Journal: Molecular cell
Published: March 03, 2025

Cell cycle regulation has shaped replication origins in budding yeast.

Cell cycle regulation has shaped replication origins in budding yeast.

Journal: Nature structural & molecular biology
Published: January 16, 2025

S-phase checkpoint protects from aberrant replication fork processing and degradation.

S-phase checkpoint protects from aberrant replication fork processing and degradation.

Journal: Nucleic acids research
Published: December 10, 2024

Mechanisms for licensing origins of DNA replication in eukaryotic cells.

Mechanisms for licensing origins of DNA replication in eukaryotic cells.

Journal: Nature structural & molecular biology
Published: November 10, 2024

Replisome passage through the cohesin ring.

Replisome passage through the cohesin ring.

Journal: Cell
Published: November 08, 2024

The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks.

The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks.

Journal: Molecular cell
Published: October 07, 2024

The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells.

The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells.

Journal: Molecular cell
Published: October 07, 2024

Author Correction: Unwinding of a eukaryotic origin of replication visualized by cryo-EM.

Author Correction: Unwinding of a eukaryotic origin of replication visualized by cryo-EM.

Journal: Nature structural & molecular biology
Published: September 09, 2024
Showing 1-12 of 68

Last Updated: 09/26/2026