John G. Woodland

Rondebosch, WC 7701, South Africa

Last Updated: 09/26/2026

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Found 30 publications

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of PfArk1 and Hemozoin Formation.

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of PfArk1 and Hemozoin Formation.

Journal: ACS chemical biology

Published: June 13, 2026

From Parasite to Pill: Harnessing Biology for Breakthroughs in Antimalarial Drug Discovery.

From Parasite to Pill: Harnessing Biology for Breakthroughs in Antimalarial Drug Discovery.

Journal: Cold Spring Harbor perspectives in medicine

Published: June 01, 2026

New thinking for the next generation of antimalarials.

New thinking for the next generation of antimalarials.

Journal: EMBO molecular medicine

Published: May 29, 2026

A university-certified course on dossier assessment for regulatory scientists in Africa-Reporting on our 5-year experience.

A university-certified course on dossier assessment for regulatory scientists in Africa-Reporting on our 5-year experience.

Journal: British journal of clinical pharmacology

Published: February 09, 2026

Bheka Thina ("Look At Us"): The Emergence of an Integrated Drug Discovery Ecosystem in South Africa.

Bheka Thina ("Look At Us"): The Emergence of an Integrated Drug Discovery Ecosystem in South Africa.

Journal: ACS medicinal chemistry letters

Published: February 05, 2026

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues.

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues.

Journal: ACS medicinal chemistry letters

Published: January 04, 2026

Fifteen Years, One Mission: Innovative, Inspirational, and Impactful Discoveries.

Fifteen Years, One Mission: Innovative, Inspirational, and Impactful Discoveries.

Journal: ACS medicinal chemistry letters

Published: November 24, 2025

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model.

Journal: Journal of medicinal chemistry

Published: August 14, 2025

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity Against Plasmodium falciparum via Dual Inhibition of PfArk1 and Hemozoin Formation.

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity Against Plasmodium falciparum via Dual Inhibition of PfArk1 and Hemozoin Formation.

Journal: bioRxiv : the preprint server for biology

Published: August 12, 2025

Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite Plasmodium falciparum.

Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite Plasmodium falciparum.

Journal: Journal of medicinal chemistry

Published: May 12, 2025

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.

Journal: Angewandte Chemie (International ed. in English)

Published: December 23, 2024

Addressing infectious diseases in Africa by accelerating drug discovery through data science.

Addressing infectious diseases in Africa by accelerating drug discovery through data science.

Journal: Communications medicine

Published: November 29, 2024

Showing 1-12 of 30

Last Updated: 09/26/2026