John H. Viles

Mile End Road
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 33 publications

3D nanoscale imaging of amyloid-β oligomer interactions with extracellular vesicles by cryo-ET.

3D nanoscale imaging of amyloid-β oligomer interactions with extracellular vesicles by cryo-ET.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 14, 2026

Amyloid-β oligomers, curvilinear and annular assemblies, imaged by cryo-ET, cryo-EM, and AFM.

Amyloid-β oligomers, curvilinear and annular assemblies, imaged by cryo-ET, cryo-EM, and AFM.

Journal: Science advances

Published: August 27, 2025

The p3 peptides (Aβ17-40/42) rapidly form amyloid fibrils that cross-seed with full-length Aβ.

The p3 peptides (Aβ17-40/42) rapidly form amyloid fibrils that cross-seed with full-length Aβ.

Journal: Nature communications

Published: June 27, 2024

Impact of Membrane Phospholipids and Exosomes on the Kinetics of Amyloid-β Fibril Assembly.

Impact of Membrane Phospholipids and Exosomes on the Kinetics of Amyloid-β Fibril Assembly.

Journal: Journal of molecular biology

Published: December 07, 2023

Copper(II) Can Kinetically Trap Arctic and Italian Amyloid-β40 as Toxic Oligomers, Mimicking Cu(II) Binding to Wild-Type Amyloid-β42: Implications for Familial Alzheimer's Disease.

Copper(II) Can Kinetically Trap Arctic and Italian Amyloid-β40 as Toxic Oligomers, Mimicking Cu(II) Binding to Wild-Type Amyloid-β42: Implications for Familial Alzheimer's Disease.

Journal: JACS Au

Published: November 06, 2023

Imaging Amyloid-β Membrane Interactions: Ion-Channel Pores and Lipid-Bilayer Permeability in Alzheimer's Disease.

Imaging Amyloid-β Membrane Interactions: Ion-Channel Pores and Lipid-Bilayer Permeability in Alzheimer's Disease.

Journal: Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Published: October 26, 2022

Imaging Amyloid-β Membrane Interactions: Ion-Channel Pores and Lipid-Bilayer Permeability in Alzheimer's Disease.

Imaging Amyloid-β Membrane Interactions: Ion-Channel Pores and Lipid-Bilayer Permeability in Alzheimer's Disease.

Journal: Angewandte Chemie (International ed. in English)

Published: October 26, 2022

pH Dependence of Amyloid-β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes.

pH Dependence of Amyloid-β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes.

Journal: Angewandte Chemie (International ed. in English)

Published: July 20, 2022

pH Dependence of Amyloid-β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes.

pH Dependence of Amyloid-β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes.

Journal: Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Published: July 20, 2022

Therapeutic potential for amyloid surface inhibitor: only amyloid-β oligomers formed by secondary nucleation disrupt lipid membrane integrity.

Therapeutic potential for amyloid surface inhibitor: only amyloid-β oligomers formed by secondary nucleation disrupt lipid membrane integrity.

Journal: The FEBS journal

Published: February 22, 2022

Cross-seeding of WT amyloid-β with Arctic but not Italian familial mutants accelerates fibril formation in Alzheimer's disease.

Cross-seeding of WT amyloid-β with Arctic but not Italian familial mutants accelerates fibril formation in Alzheimer's disease.

Journal: The Journal of biological chemistry

Published: December 06, 2021

3D-visualization of amyloid-β oligomer interactions with lipid membranes by cryo-electron tomography.

3D-visualization of amyloid-β oligomer interactions with lipid membranes by cryo-electron tomography.

Journal: Chemical science

Published: June 14, 2021

Showing 1-12 of 33

Last Updated: 09/26/2026