John K. Wee

10 Biopolis Road, #05-01
Singapore, 138670, Singapore

Last Updated: 09/26/2026

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Found 14 publications

Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*.

Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*.

Journal: Angewandte Chemie (International ed. in English)
Published: April 20, 2021

Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.

Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.

Journal: Journal of medicinal chemistry
Published: January 08, 2020

Correction to "Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3".

Correction to "Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3".

Journal: ACS medicinal chemistry letters
Published: August 16, 2019

Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.

Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.

Journal: ACS medicinal chemistry letters
Published: April 15, 2019

Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia.

Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia.

Journal: Journal of medicinal chemistry
Published: April 24, 2018

Discovery and characterisation of the automethylation properties of PRDM9.

Discovery and characterisation of the automethylation properties of PRDM9.

Journal: The Biochemical journal
Published: December 06, 2016

Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease.

Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease.

Journal: Journal of enzyme inhibition and medicinal chemistry
Published: June 01, 2016

Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells.

Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells.

Journal: Journal of medicinal chemistry
Published: March 25, 2016

Identification of covalent active site inhibitors of dengue virus protease.

Identification of covalent active site inhibitors of dengue virus protease.

Journal: Drug design, development and therapy
Published: December 18, 2015

Antiviral activities of 15 dengue NS2B-NS3 protease inhibitors using a human cell-based viral quantification assay.

Antiviral activities of 15 dengue NS2B-NS3 protease inhibitors using a human cell-based viral quantification assay.

Journal: Antiviral research
Published: October 30, 2014

Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques.

Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques.

Journal: The Biochemical journal
Published: May 03, 2014

A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides.

A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides.

Journal: Peptides
Published: August 31, 2013
Showing 1-12 of 14

Last Updated: 09/26/2026