John L. Kiappes
Oxford, ENG OX13QU, United Kingdom
Last Updated: 09/26/2026
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Found 13 publications
Assessment of repurposed compounds against coronaviruses highlights the antiviral broad-spectrum activity of host-targeting iminosugars and confirms the activity of potent directly acting antivirals.
Journal: Antiviral research
Published: October 22, 2024
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Journal: Science (New York, N.Y.)
Published: November 09, 2023
N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity.
Journal: Journal of medicinal chemistry
Published: December 06, 2021
Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike.
Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike.
Journal: ACS central science
Published: January 14, 2021
Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections.
Journal: Journal of medicinal chemistry
Published: April 02, 2020
Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II.
Journal: Advances in experimental medicine and biology
Published: May 31, 2018
ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity.
Journal: ACS chemical biology
Published: November 22, 2017
Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 28, 2016
Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4.
Journal: Antiviral research
Published: December 10, 2015
Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases--Not Glycolipid Processing Enzymes.
Journal: PLoS neglected tropical diseases
Published: November 06, 2015
Last Updated: 09/26/2026