John R. Perfect

John R. Perfect

Infectious Disease
40 Duke Medicine Cir
Durham, NC 27710

Last Updated: 09/26/2026

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Found 231 publications

Closing the gap on antifungal resistance.

Closing the gap on antifungal resistance.

Journal: Nature medicine
Published: April 15, 2026

MUC16-dependent Renal Vascular Adhesion of Candida Promotes Tissue Invasion and Predicts Clinical Outcome in Candidemia.

MUC16-dependent Renal Vascular Adhesion of Candida Promotes Tissue Invasion and Predicts Clinical Outcome in Candidemia.

Journal: Research square
Published: March 16, 2026

In vitro evidence to support amphotericin B and flucytosine combination therapy for talaromycosis.

In vitro evidence to support amphotericin B and flucytosine combination therapy for talaromycosis.

Journal: PLoS neglected tropical diseases
Published: October 15, 2025

Multisystem Lomentospora prolificans progression on fosmanogepix despite in vitro activity: a call for expanding clinical research on novel antifungals.

Multisystem Lomentospora prolificans progression on fosmanogepix despite in vitro activity: a call for expanding clinical research on novel antifungals.

Journal: ASM case reports
Published: October 11, 2025

In Vitro Evidence to Support Amphotericin B and Flucytosine Combination Therapy for Talaromycosis.

In Vitro Evidence to Support Amphotericin B and Flucytosine Combination Therapy for Talaromycosis.

Journal: bioRxiv : the preprint server for biology
Published: October 03, 2025

Vaccine-Mediated Protection of Mice Against African and Asian Clinical Strains of Cryptococcus neoformans.

Vaccine-Mediated Protection of Mice Against African and Asian Clinical Strains of Cryptococcus neoformans.

Journal: Journal of fungi (Basel, Switzerland)
Published: September 29, 2025

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways.

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways.

Journal: mBio
Published: August 25, 2025

Temperature and genetic background drive mobilization of diverse transposable elements in a global human fungal pathogen.

Temperature and genetic background drive mobilization of diverse transposable elements in a global human fungal pathogen.

Journal: PLoS genetics
Published: August 18, 2025

Temperature and genetic background drive mobilization of diverse transposable elements in a critical human fungal pathogen.

Temperature and genetic background drive mobilization of diverse transposable elements in a critical human fungal pathogen.

Journal: bioRxiv : the preprint server for biology
Published: June 06, 2025

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways.

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways.

Journal: bioRxiv : the preprint server for biology
Published: May 15, 2025

The Pain Is in the Brain With the Sugar-Coated Killer.

The Pain Is in the Brain With the Sugar-Coated Killer.

Journal: The Journal of infectious diseases
Published: April 01, 2025

Genome restructuring and lineage diversification of Cryptococcus neoformans during chronic infection of human hosts.

Genome restructuring and lineage diversification of Cryptococcus neoformans during chronic infection of human hosts.

Journal: medRxiv : the preprint server for health sciences
Published: March 04, 2025
Showing 1-12 of 231

Last Updated: 09/26/2026