John W. Creemers

Leuven, VLG, Belgium

Last Updated: 09/26/2026

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Found 62 publications

The Role of Furin in Hallmarks of Aneurysms: A Focus On Its Substrates.

The Role of Furin in Hallmarks of Aneurysms: A Focus On Its Substrates.

Journal: Current atherosclerosis reports
Published: January 04, 2026

Furin-like enzyme dependency in KRAS-mutant colorectal cancer as a target for personalized treatment strategies.

Furin-like enzyme dependency in KRAS-mutant colorectal cancer as a target for personalized treatment strategies.

Journal: Biochimica et biophysica acta. Reviews on cancer
Published: December 19, 2025

Furin sustains tumor-promoting signals in KRAS- and BRAF-mutated colorectal cancer by engaging the TGF-β1-COX-2 axis in a reciprocal regulatory network.

Furin sustains tumor-promoting signals in KRAS- and BRAF-mutated colorectal cancer by engaging the TGF-β1-COX-2 axis in a reciprocal regulatory network.

Journal: Oncogene
Published: September 16, 2025

Erythroid-produced intact FGF23 is a paracrine inhibitor of erythropoiesis.

Erythroid-produced intact FGF23 is a paracrine inhibitor of erythropoiesis.

Journal: Blood
Published: July 01, 2025

Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions.

Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions.

Journal: JCI insight
Published: January 11, 2024

Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome.

Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome.

Journal: Biochimica et biophysica acta. Molecular basis of disease
Published: December 18, 2023

Unveiling the oncogenic role of LZTS1 in colorectal cancer.

Unveiling the oncogenic role of LZTS1 in colorectal cancer.

Journal: Journal of cellular and molecular medicine
Published: November 15, 2023

Epigenetic modulations of immune cells: from normal development to tumor progression.

Epigenetic modulations of immune cells: from normal development to tumor progression.

Journal: International journal of biological sciences
Published: July 21, 2023

The proprotein convertase FURIN is a novel aneurysm predisposition gene impairing TGF-β signalling.

The proprotein convertase FURIN is a novel aneurysm predisposition gene impairing TGF-β signalling.

Journal: Cardiovascular research
Published: May 31, 2023

Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation.

Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation.

Journal: Blood
Published: October 26, 2022

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice.

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice.

Journal: Molecular metabolism
Published: July 08, 2022

The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance.

The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance.

Journal: iScience
Published: May 12, 2022
Showing 1-12 of 62

Last Updated: 09/26/2026