Jonathan C. Makielski

Cardiology

600 Highland Ave
Madison,, WI 53792

Last Updated: 09/26/2026

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Found 44 publications

Expression Defects of SCN5A Common Polymorphisms S524Y and H558R in the Q1077 Splice Variant Can Be Rescued by Mexiletine.

Expression Defects of SCN5A Common Polymorphisms S524Y and H558R in the Q1077 Splice Variant Can Be Rescued by Mexiletine.

Journal: Cells

Published: May 31, 2026

Does Anatomic Phenotype of Mitral Annular Disjunction Impact Survival? An Autopsy-Based Retrospective Study.

Does Anatomic Phenotype of Mitral Annular Disjunction Impact Survival? An Autopsy-Based Retrospective Study.

Journal: Journal of cardiovascular development and disease

Published: October 27, 2021

Caveolin-3 and Caveolae regulate ventricular repolarization.

Caveolin-3 and Caveolae regulate ventricular repolarization.

Journal: Journal of molecular and cellular cardiology

Published: July 02, 2021

Expression defect of the rare variant/Brugada mutation R1512W depends upon the SCN5A splice variant background and can be rescued by mexiletine and the common polymorphism H558R.

Expression defect of the rare variant/Brugada mutation R1512W depends upon the SCN5A splice variant background and can be rescued by mexiletine and the common polymorphism H558R.

Journal: Channels (Austin, Tex.)

Published: February 04, 2021

Genetic Loss of IK1 Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia.

Genetic Loss of IK1 Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia.

Journal: Circulation. Arrhythmia and electrophysiology

Published: September 15, 2020

Association of Mitral Annular Disjunction With Premature Cardiac Mortality in a Large Series of Autopsies.

Association of Mitral Annular Disjunction With Premature Cardiac Mortality in a Large Series of Autopsies.

Journal: Journal of the American College of Cardiology

Published: June 23, 2020

Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts.

Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts.

Journal: Biotechnology and bioengineering

Published: May 11, 2020

A Singular Signature.

A Singular Signature.

Journal: Circulation

Published: November 12, 2019

Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective.

Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective.

Journal: JACC. Basic to translational science

Published: October 19, 2018

Mexiletine rescues a mixed biophysical phenotype of the cardiac sodium channel arising from the SCN5A mutation, N406K, found in LQT3 patients.

Mexiletine rescues a mixed biophysical phenotype of the cardiac sodium channel arising from the SCN5A mutation, N406K, found in LQT3 patients.

Journal: Channels (Austin, Tex.)

Published: July 10, 2018

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function.

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function.

Journal: Heliyon

Published: May 04, 2018

An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population.

An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population.

Journal: Journal of the American Heart Association

Published: April 05, 2017

Showing 1-12 of 44

Last Updated: 09/26/2026