Jonathan M. Cairns

R&D, AstraZeneca, Trumpington
Cambridge, ENG CB20AA, United Kingdom

Last Updated: 09/26/2026

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Found 25 publications

Correction: A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

Correction: A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

Journal: PloS one
Published: March 20, 2025

AutoFlow: an interactive Shiny app for supervised and unsupervised flow cytometry analysis.

AutoFlow: an interactive Shiny app for supervised and unsupervised flow cytometry analysis.

Journal: Bioinformatics (Oxford, England)
Published: December 31, 2024

A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

Journal: PloS one
Published: May 06, 2024

Impact of the physical-chemical properties of poly(lactic acid)-poly(ethylene glycol) polymeric nanoparticles on biodistribution.

Impact of the physical-chemical properties of poly(lactic acid)-poly(ethylene glycol) polymeric nanoparticles on biodistribution.

Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: June 30, 2023

The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.

The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.

Journal: Cancer research
Published: March 03, 2023

Optimal experimental design for efficient toxicity testing in microphysiological systems: A bone marrow application.

Optimal experimental design for efficient toxicity testing in microphysiological systems: A bone marrow application.

Journal: Frontiers in pharmacology
Published: January 11, 2023

High-Throughput Mechanism of Inhibition.

High-Throughput Mechanism of Inhibition.

Journal: SLAS discovery : advancing life sciences R & D
Published: January 22, 2021

Detecting chromosomal interactions in Capture Hi-C data with CHiCAGO and companion tools.

Detecting chromosomal interactions in Capture Hi-C data with CHiCAGO and companion tools.

Journal: Nature protocols
Published: September 10, 2020

The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle.

The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle.

Journal: Genome biology
Published: August 20, 2020

Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development.

Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development.

Journal: Molecular cancer therapeutics
Published: June 19, 2020

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.

Journal: Nature communications
Published: March 28, 2019

Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data.

Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data.

Journal: Bioinformatics (Oxford, England)
Published: January 22, 2019
Showing 1-12 of 25

Last Updated: 09/26/2026